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Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c01578
Abstract: A catalytic asymmetric umpolung cross-Mannich reaction of cyclic ketimines is realized. This protocol provides an efficient methodology for the facile synthesis of chiral vicinal tetrasubstituted diamines in high yields with excellent chemo-, regio-, diastereo-, and…
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Keywords:
mannich reaction;
reaction cyclic;
cyclic ketimines;
umpolung cross ... See more keywords