AI-Driven Tools for Coronavirus Outbreak: Need of Active Learning and Cross-Population Train/Test Models on Multitudinal/Multimodal Data
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Systems"
DOI: 10.1007/s10916-020-01562-1
Abstract: The novel coronavirus (COVID-19) outbreak, which was identified in late 2019, requires special attention because of its future epidemics and possible global threats. Beside clinical procedures and treatments, since Artificial Intelligence (AI) promises a new… read more here.
Keywords: driven tools; active learning; population train; train test ... See more keywords
A unified framework for cross-population trait prediction by leveraging the genetic correlation of polygenic traits.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.03.002
Abstract: The development of polygenic risk scores (PRSs) has proved useful to stratify the general European population into different risk groups. However, PRSs are less accurate in non-European populations due to genetic differences across different populations.… read more here.
Keywords: framework; polygenic; genetic correlation; cross population ... See more keywords
XPXP: improving polygenic prediction by cross-population and cross-phenotype analysis
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac029
Abstract: MOTIVATION As increasing sample sizes from genome-wide association studies (GWASs), polygenic risk scores (PRSs) have shown great potential in personalized medicine with disease risk prediction, prevention and treatment. However, the PRS constructed using European samples… read more here.
Keywords: phenotype; cross; analysis; xpxp ... See more keywords
Multi-trait and cross-population genome-wide association studies across autoimmune and allergic diseases identify shared and distinct genetic component
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2022-222460
Abstract: Objectives Autoimmune and allergic diseases are outcomes of the dysregulation of the immune system. Our study aimed to elucidate differences or shared components in genetic backgrounds between autoimmune and allergic diseases. Methods We estimated genetic… read more here.
Keywords: multi trait; autoimmune allergic; allergic diseases; trait cross ... See more keywords
Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations
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DOI: 10.1371/journal.pgen.1009695
Abstract: Facial morphology is highly variable, both within and among human populations, and a sizable portion of this variation is attributable to genetics. Previous genome scans have revealed more than 100 genetic loci associated with different… read more here.
Keywords: variation; genetics; genome scans; cross population ... See more keywords
Analysis of cross-population differentiation between Thoroughbred and Jeju horses
Sign Up to like & getrecommendations! Published in 2018 at "Asian-Australasian Journal of Animal Sciences"
DOI: 10.5713/ajas.17.0460
Abstract: Objective This study was intended to identify genes positively selected in Thoroughbred horses (THBs) that potentially contribute to their running performances. Methods The genomes of THB and Jeju horses (JH, Korean native horse) were compared… read more here.
Keywords: jeju horses; analysis; cross population; size ... See more keywords