A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours
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DOI: 10.1038/s41565-021-00988-z
Abstract: Activating CD8+ T cells by antigen cross-presentation is remarkably effective at eliminating tumours. Although this function is traditionally attributed to dendritic cells, tumour-associated macrophages (TAMs) can also cross-present antigens. TAMs are the most abundant tumour-infiltrating… read more here.
Keywords: cd8; cd8 cells; present antigens; cross present ... See more keywords