Cross‐reactive cellular, but not humoral, immunity is detected between OC43 and SARS‐CoV‐2 NPs in people not infected with SARS‐CoV‐2: Possible role of cTFH cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4covcra0721-356rrr
Abstract: Multiple questions about SARS‐CoV‐2 humoral and cellular immunity remain unanswered. One key question is whether preexisting memory T or B cells, specific for related coronaviruses in SARS‐CoV‐2‐unexposed individuals, can recognize and suppress COVID‐19, but this… read more here.
Keywords: oc43 sars; cell; immunity; cross reactive ... See more keywords
A public, cross-reactive glycoprotein epitope confounds Ebola virus serology
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medical virology"
DOI: 10.1002/jmv.29946
Abstract: Ebola disease (EBOD) in humans is a severe disease caused by at least four related viruses in the genus Orthoebolavirus, most often by the eponymous Ebola virus. Due to human‐to‐human transmission and incomplete success in… read more here.
Keywords: cross reactive; virus; epitope; serology ... See more keywords
Identification of Major and Cross-reactive Allergens of Local Freshwater Snail (Pila polita) and the Impact of Thermal and Non-thermal Food Processing on Allergen Stability.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12659
Abstract: BACKGROUND Snail allergy is rare but can be fatal. Pila polita, a freshwater snail was considered as a popular exotic food particularly in tropical countries and consumed in processed forms. Thus, the purpose of this… read more here.
Keywords: food; reactive allergens; cross reactive; snail ... See more keywords
Computational identification of cross-reactive TCR epitopes with ARDitox
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-025-06330-7
Abstract: Cellular immunotherapies, such as those utilizing T lymphocytes expressing native or engineered T cell receptors (TCRs), have demonstrated therapeutic efficacy. However, some engineered high-affinity TCRs have caused fatal off-target immunotoxicity due to targeting epitopes later… read more here.
Keywords: computational identification; tcr; target; cross reactive ... See more keywords
Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress
Sign Up to like & getrecommendations! Published in 2021 at "Cell"
DOI: 10.1016/j.cell.2021.07.033
Abstract: Alphaviruses cause severe arthritogenic or encephalitic disease. The E1 structural glycoprotein is highly conserved in these viruses and mediates viral fusion with host cells. However, the role of antibody responses to the E1 protein in… read more here.
Keywords: alphavirus cross; cross reactive; therapeutic alphavirus; egress therapeutic ... See more keywords
P175 Flow cytometry using monoclonal antibody for detection of HLA-B27: Analysis of ‘Gray Zone’ results for cross reactive antigens
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.235
Abstract: Aim HLA-B27 (associated with ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter’s syndrome) can be detected utilizing monoclonal antibodies. This assay is a simple qualitative two-color direct immunofluorescence flow cytometric method for rapid detection of the… read more here.
Keywords: gray zone; hla b27; cross reactive; hla ... See more keywords
The avidity of cross-reactive virus-specific T cells for their viral and allogeneic epitopes is variable and depends on epitope expression.
Sign Up to like & getrecommendations! Published in 2018 at "Human immunology"
DOI: 10.1016/j.humimm.2017.10.019
Abstract: Virus-specific T cells can recognize allogeneic HLA (allo-HLA) through cross-reactivity of their T-cell receptor (TCR). In a transplantation setting, such allo-HLA cross-reactivity may contribute to harmful immune responses towards the allograft, provided that the cross-reactive… read more here.
Keywords: allo hla; cross; cross reactive; virus specific ... See more keywords
Staggered Target SELEX, a novel approach to isolate non-cross-reactive aptamer for detection of SEA by apta-qPCR.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2018.09.006
Abstract: BACKGROUND AND OBJECTIVE Aptamers or chemical antibodies are oligonucleotides (DNA or RNA) that are able to bind to various targets with high specificity and affinity such as toxins which are isolated by an in vitro… read more here.
Keywords: apta qpcr; protein; detection; sea ... See more keywords
Identification of monoclonal antibodies cross-reactive with bottlenose dolphin orthologues of the major histocompatibility complex and leukocyte differentiation molecules.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2017.09.007
Abstract: The slow progress in understanding immunotoxic effects of environmental contaminants and their influence on disease susceptibility in whales is largely due to the limited information available on the immune systems and immune function of species… read more here.
Keywords: differentiation molecules; leukocyte differentiation; histocompatibility complex; cross reactive ... See more keywords
Cross-Reactive Fluorescent Sensor Array for Discrimination of Amyloid Beta Aggregates.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00579
Abstract: It has been hypothesized that misfolding and misassembly of proteins into various aggregation states contribute to several neurodegenerative diseases. For instance, amyloid beta (Aβ) aggregation is considered a major factor in Alzheimer's disease pathogenesis. Herein,… read more here.
Keywords: amyloid beta; fluorescent sensor; cross reactive; sensor array ... See more keywords
Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+ T cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Microbiology"
DOI: 10.1038/nmicrobiol.2017.36
Abstract: CD8+ T cells play an important role in controlling Flavivirus infection, including Zika virus (ZIKV). Here, we have identified 25 HLA-B*0702-restricted epitopes and 1 HLA-A*0101-restricted epitope using interferon (IFN)-γ enzyme-linked immunospot (ELISPOT) and intracellular cytokine… read more here.
Keywords: cd8; cd8 cells; zikv; cross reactive ... See more keywords