Mixed‐Up Sugars: Glycosyltransferase Cross‐Reactivity in Cancerous Tissues and Their Therapeutic Targeting
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202100460
Abstract: The main categories of glycan changes in cancer are: (1) decreased expression of histo‐blood group A and/or B antigens and increased Lewis‐related antigens, (2) appearance of cryptic antigens, such as Tn and T, (3) emergence of genetically incompatible… read more here.
Keywords: mixed sugars; glycosyltransferase cross; cancerous tissues; sugars glycosyltransferase ... See more keywords
Cross‐reactivity between tick and wasp venom can contribute to frequent wasp sensitization in patients with the α‐Gal syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12113
Abstract: Abstract Background α‐Gal syndrome (AGS) is a food allergy with severe delayed allergic reactions, mediated by IgE‐reactivity to galactose‐α1,3‐galactose (α‐Gal). AGS is strongly associated with tick bites. An increased incidence of venom sensitization has been… read more here.
Keywords: wasp venom; venom; reactivity; cross reactivity ... See more keywords
DRESS syndrome: A case of cross‐reactivity with lacosamide?
Sign Up to like & getrecommendations! Published in 2017 at "Epilepsia Open"
DOI: 10.1002/epi4.12053
Abstract: A 42‐year‐old patient with epilepsy was admitted to the hospital for fever and generalized skin rash. He has known allergy to phenytoin. Valproate was started in 2012, but failed to control his seizure despite gradual… read more here.
Keywords: dress syndrome; cross reactivity; reactivity lacosamide;
Co‐sensitization and cross‐reactivity of Blomia tropicalis with two Dermatophagoides species in Guangzhou, China
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DOI: 10.1002/jcla.22981
Abstract: Contradictory results have been reported previously in the analyses of cross‐reactivity among Blomia tropicalis (Blo t), Dermatophagoides pteronyssinus (Der p), and Dermatophagoides farinae (Der f). This study aims to investigate the characteristics of co‐sensitization and… read more here.
Keywords: reactivity; cross reactivity; sensitization; blomia tropicalis ... See more keywords
Cross reactivity of commercial anti‐dengue immunoassays in patients with acute Zika virus infection
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24789
Abstract: Several countries have local transmission of multiple arboviruses, in particular, dengue and Zika viruses, which have recently spread through many American countries. Cross reactivity among Flaviviruses is high and present a challenge for accurate identification… read more here.
Keywords: dengue; cross reactivity; infection; anti dengue ... See more keywords
Antibody Colocalization Microarray for Cross-Reactivity-Free Multiplexed Protein Analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7057-5_19
Abstract: Measuring many proteins at once is of great importance to the idea of personalized medicine, in order to get a snapshot of a person's health status. We describe the antibody colocalization microarray (ACM), a variant of… read more here.
Keywords: cross reactivity; antibody; antibody colocalization; colocalization microarray ... See more keywords
Cross-Reactivity of Alpha-Synuclein with Other Cellular Components Can Dramatically Modulate Amyloid Formation
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1980
Abstract: The aggregation process, going from monomers to amyloid fibers, of the protein α-synuclein (αS) somehow causes degeneration of dopaminergic neurons in Parkinson's disease patients. The exact activities of αS are not yet identified, but synapse… read more here.
Keywords: cross reactivity; modulate amyloid; formation; parkinson disease ... See more keywords
Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.109164
Abstract: A major goal of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope targets of the SARS-CoV-2 antibody response is critical for vaccine… read more here.
Keywords: cross reactivity; response; reactivity endemic; endemic human ... See more keywords
Limited cross reactivity among arginine kinase allergens from mealworm and cricket edible insects.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2018.10.082
Abstract: Insects are seen as a solution to the increasing demand for protein sources for food. However, entomophagy has unfortunately been linked to allergic reactions in Europe with people with professional contacts. As mealworms (Tenebrio molitor)… read more here.
Keywords: insects; cross reactivity; limited cross; arginine kinase ... See more keywords
Validation and cross-reactivity pattern assessment of monoclonal antibodies used for the screening of donor-specific IgG antibody subclasses in transplant recipients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2020.112847
Abstract: The screening for IgG subclass donor-specific antibodies (DSAs) in allograft recipients uses IgG1-4 subclass-specific monoclonal antibodies (mAbs) that should be mono-specific. The cross-reactivity discrepancies reported for IgG subclass-specific mAbs warranted a critical cross-reactivity pattern analysis… read more here.
Keywords: subclass specific; igg subclass; subclass; cross reactivity ... See more keywords
Improved serodiagnosis of histoplasmosis by use of deglycosylated extracellular released antigens of Histoplasma capsulatum.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of microbiological methods"
DOI: 10.1016/j.mimet.2020.105981
Abstract: The diagnosis of histoplasmosis depends on various approaches: direct clinical examination, fungus isolation from cultures of clinical samples, histopathological evaluation, and serological testing. In serodiagnostic assays, the Histoplasma capsulatum H and M antigenic glycoproteins have… read more here.
Keywords: cross reactivity; capsulatum; extracellular released; deglycosylated extracellular ... See more keywords