Comprehensive identification of pleiotropic loci for body fat distribution using the NHGRI‐EBI Catalog of published genome‐wide association studies
Sign Up to like & getrecommendations! Published in 2019 at "Obesity Reviews"
DOI: 10.1111/obr.12806
Abstract: We conducted a hypothesis‐free cross‐trait analysis for waist‐to‐hip ratio adjusted for body mass index (WHRadjBMI) loci derived through genome‐wide association studies (GWAS). Summary statistics from published GWAS were used to capture all WHRadjBMI single‐nucleotide polymorphisms… read more here.
Keywords: genome wide; cross trait; snps; association ... See more keywords
Shared Genetic Architecture and Causal Relationship Between Asthma and Cardiovascular Diseases: A Large-Scale Cross-Trait Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.775591
Abstract: Background: Accumulating evidence has suggested that there is a positive association between asthma and cardiovascular diseases (CVDs), implying a common architecture between them. However, the shared genetic architecture and causality of asthma and CVDs remain… read more here.
Keywords: cross trait; shared genetic; causal relationship; relationship asthma ... See more keywords