LAUSR: crossed allele

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Development of duplex-crossed allele-specific PCR targeting of TPMT3B and 3C using crossed allele-specific blockers to eliminate non-specific amplification.

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0 Published in 2019 at "Analytical biochemistry"

DOI: 10.1016/j.ab.2019.03.019

Abstract: Prospective testing for variants in the thiopurine S-methyltransferase (TPMT) is considered a key process in the development of thiopurine therapy. This testing is done to avoid toxicity and side effects in the management of diverse… read more here.

Keywords: non specific; specific amplification; crossed allele; pcr ... See more keywords

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Development of duplex-crossed allele-specific PCR targeting of TPMT3B and 3C using crossed allele-specific blockers to eliminate non-specific amplification.

Development of duplex-crossed allele-specific PCR targeting of TPMT*3B and *3C using crossed allele-specific blockers to eliminate non-specific amplification.

Development of duplex-crossed allele-specific PCR targeting of TPMT3B and 3C using crossed allele-specific blockers to eliminate non-specific amplification.