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Eltrombopag, a thrombopoietin mimetic, crosses the blood–brain barrier and impairs iron‐dependent hippocampal neuron dendrite development

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Published in 2017 at "Journal of Thrombosis and Haemostasis"

DOI: 10.1111/jth.13602

Abstract: Essentials Potential neurodevelopmental side effects of thrombopoietin mimetics need to be considered. The effects of eltrombopag (ELT) on neuronal iron status and dendrite development were assessed. ELT crosses the blood–brain barrier and causes iron deficiency… read more here.

Keywords: blood brain; iron; brain barrier; dendrite development ... See more keywords