Elastoplastic behavior of anisotropic, physically crosslinked hydrogel networks comprising stiff, charged fibrils in an electrolyte.
Sign Up to like & getrecommendations! Published in 2023 at "Soft matter"
DOI: 10.1039/d2sm01571d
Abstract: Fibrillar hydrogels are remarkably stiff, low-density networks that can hold vast amounts of water. These hydrogels can easily be made anisotropic by orienting the fibrils using different methods. Unlike the detailed and established descriptions of… read more here.
Keywords: crosslinked hydrogel; physically crosslinked; anisotropic physically; behavior anisotropic ... See more keywords
In Situ Crosslinked Hydrogel Depot for Sustained Antibody Release Improves Immune Checkpoint Blockade Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2021 at "Nanomaterials"
DOI: 10.3390/nano11020471
Abstract: The therapeutic inhibition of immune checkpoints, including cytotoxic T lymphocyte-associated protein (CTLA)-4 and programmed cell death 1 (PD-1), through the use of function blocking antibodies can confer improved clinical outcomes by invigorating CD8+ T cell-mediated… read more here.
Keywords: checkpoint blockade; immune checkpoint; crosslinked hydrogel; situ crosslinked ... See more keywords