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Published in 2025 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1591
Abstract: Clevidipine emulsion is an intravenous antihypertensive agent indicated for acute blood pressure control when oral therapies are contraindicated or ineffective. To address this gap in availability, a randomized, 2‐period, 2‐sequence crossover trial was conducted to…
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Keywords:
healthy chinese;
period;
bioequivalence;
study ... See more keywords
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Published in 2021 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25561
Abstract: In mechanically ventilated patients, driving pressure (ΔP) represents the dynamic stress applied to the respiratory system and is related to ICU mortality. An evolution of the Adaptive Support Ventilation algorithm (ASV® 1.1) minimizes inspiratory pressure…
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Keywords:
crossover trial;
mode;
ventilation;
randomized crossover ... See more keywords
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Published in 2021 at "Journal of Nutritional Science"
DOI: 10.1017/jns.2021.70
Abstract: Abstract The aim of the study was to investigate the effect of prebiotic fibres on appetite-regulating hormones, subjective feeling of appetite and energy intake in subjects with type 2 diabetes. Data presented are secondary outcomes…
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Keywords:
crossover trial;
controlled crossover;
inulin type;
effect ... See more keywords
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Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47630-6
Abstract: Defibrotide is approved for the treatment of sinusoidal obstruction syndrome after allogeneic stem cell transplantation. The exact mode of action of defibrotide is unclear and human in vivo data are scarce. In this randomized, double…
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Keywords:
crossover trial;
randomized double;
healthy volunteers;
blind crossover ... See more keywords
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Published in 2025 at "Annals of Medicine"
DOI: 10.1080/07853890.2025.2517819
Abstract: Abstract Background Postoperative nausea and vomiting (PONV) are common complications after surgery. Opioid use is a significant risk factor. We utilised a crossover design to test this hypothesis in the same individuals that opioid-free anaesthesia…
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Keywords:
surgery;
lower extremity;
crossover trial;
anaesthesia ... See more keywords
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Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz035.p12-018-19
Abstract: Objectives To evaluate the effect of consuming ¾ cup/day of mixed dried fruits versus a calorie- and carbohydrate-matched snack, on vascular health in adults at risk for cardiometabolic disease. Methods Men and women (n = 55) with…
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Keywords:
fruit;
randomized crossover;
treatment;
dried fruit ... See more keywords
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Published in 2019 at "Current Developments in Nutrition"
DOI: 10.1093/cdn/nzz044.p08-103-19
Abstract: Elevated circulating non-fasting triglyceride (TG) or postprandial triglyceride (ppTG) is as an independent contributor to risk for coronary heart disease.We hypothesized that a commonly consumed fried meal (including French fries and chicken nuggets) prepared by…
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Keywords:
crossover trial;
meal prepared;
randomized crossover;
meal ... See more keywords
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Published in 2025 at "SLEEP"
DOI: 10.1093/sleep/zsaf090.0158
Abstract: Among shift workers, there is an increased prevalence of mood-related disorders. Our previous work showed that simulated night shifts adversely affect mood. We have also shown that daytime meal intake only, versus daytime and nighttime,…
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Keywords:
late versus;
late eating;
mood;
meal timing ... See more keywords
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Published in 2022 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.14074
Abstract: Albumin for intravenous infusion is marketed in two concentrations, 20% and 5%, but how they compare with regard to plasma volume expansion over time is unclear.
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Keywords:
albumin controlled;
kinetics albumin;
crossover trial;
controlled crossover ... See more keywords
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Published in 2025 at "Journal of Sleep Research"
DOI: 10.1111/jsr.70002
Abstract: This double‐blind, placebo‐controlled, two‐way crossover trial evaluated the efficacy and safety of daridorexant in patients with chronic insomnia and comorbid nocturia. In total, 60 patients aged ≥55 years with insomnia complaints for ≥3 months, Insomnia Severity Index…
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Keywords:
chronic insomnia;
placebo;
daridorexant treatment;
insomnia nocturia ... See more keywords
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Published in 2025 at "BMC Medical Education"
DOI: 10.1186/s12909-025-06990-6
Abstract: To make reasonable future medical decisions, medical students need to be sufficiently educated to interpret diagnostic tests. Natural frequencies are considered the gold standard for understanding single diagnostic test results. However, they may be less…
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Keywords:
likelihood ratios;
preregistered randomized;
crossover trial;
natural frequencies ... See more keywords