A novel synthetic peptide inspired on Lys49 phospholipase A2 from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.02.055
Abstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics are increasing, while alternative medicines are drying up, which urges the need to discover novel agents able to kill antibiotic-resistant bacteria. Lys49 phospholipase… read more here.
Keywords: lys49 phospholipase; abyssus snake; oreganus abyssus; resistant clinical ... See more keywords
Using Ecological Niche Models for Population and Range Estimates of a Threatened Snake Species (Crotalus oreganus) in Canada
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DOI: 10.3390/d13100467
Abstract: Modelling the distribution and abundance of species at risk is extremely important for their conservation and management. We used ecological niche models (ENMs) to predict the occurrence of western rattlesnakes (Crotalus oreganus) in British Columbia… read more here.
Keywords: ecological niche; niche models; conservation; crotalus oreganus ... See more keywords
Myotoxin-3 from the Pacific Rattlesnake Crotalus oreganus oreganus Venom Is a New Microtubule-Targeting Agent
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238241
Abstract: Microtubule targeting agents (MTA) are anti-cancer molecules that bind tubulin and interfere with the microtubule functions, eventually leading to cell death. In the present study, we used an in vitro microtubule polymerization assay to screen… read more here.
Keywords: microtubule targeting; rattlesnake crotalus; pacific rattlesnake; microtubule ... See more keywords