A Native CPP from Rattlesnake with Therapeutic and Theranostic Properties.
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DOI: 10.1007/978-1-0716-1752-6_6
Abstract: The cell-penetrating peptides (CPPs) are characterized by the ability of internalization into cells in vitro and in vivo, and the ability of these peptides can rely on a high content of positive charges, as it… read more here.
Keywords: native cpp; rattlesnake therapeutic; cpp rattlesnake; crotamine ... See more keywords
Mechanistic insights into functional characteristics of native crotamine
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DOI: 10.1016/j.toxicon.2018.03.007
Abstract: &NA; The chemical composition of snake venoms is a complex mixture of proteins and peptides that can be pharmacologically active. Crotamine, a cell‐penetrating peptide, has been described to have antimicrobial properties and it exerts its… read more here.
Keywords: mgr mgr; platelet aggregation; crotamine; mgr ... See more keywords
Effects of the Natural Peptide Crotamine from a South American Rattlesnake on Candida auris, an Emergent Multidrug Antifungal Resistant Human Pathogen
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DOI: 10.3390/biom9060205
Abstract: Invasive Candida infections are an important growing medical concern and treatment options are limited to a few antifungal drug classes, with limited efficacies depending on the infecting organism. In this scenario, invasive infections caused by… read more here.
Keywords: south american; candida; american rattlesnake; candida auris ... See more keywords