Influence of protein crowder size on hydration structure and dynamics in macromolecular crowding
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2017.01.012
Abstract: Abstract We investigate the effects of protein crowder sizes on hydration structure and dynamics in macromolecular crowded systems by all-atom MD simulations. The crowded systems consisting of only small proteins showed larger total surface areas… read more here.
Keywords: protein crowder; dynamics macromolecular; structure dynamics; crowder ... See more keywords
GB1 Dimerization in Crowders: A Multiple Resolution Approach
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.3c00012
Abstract: In-cell protein-protein association, which is crucial in enzyme catalysis and polymerization, occurs in an environment that is highly heterogeneous and crowded. The crowder molecules exclude the reactant molecules from occupying certain regions of the cell,… read more here.
Keywords: resolution model; crowder; protein association; dimerization ... See more keywords