Molecular Crowding Evolution Enables Discovery of Enthalpy-Driven Aptamers for Robust Biomedical Applications.
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DOI: 10.1021/acs.analchem.9b02697
Abstract: Enthalpy-driven ligands are ideal probes for biomedical applications because of the formation of more bonds between the ligand and target, compared to entropy-driven ligands with similar Gibbs free energy changes. However, there has been a… read more here.
Keywords: driven aptamers; enthalpy driven; molecular crowding; crowding selex ... See more keywords