Containment of a Verona Integron-Encoded Metallo-Beta-Lactamase-Producing Pseudomonas aeruginosa Outbreak Associated With an Acute Care Hospital Sink—Tennessee, 2018–2020
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DOI: 10.1093/ofid/ofad194
Abstract: Abstract Background Contaminated healthcare facility wastewater plumbing is recognized as a source of carbapenemase-producing organism transmission. In August 2019, the Tennessee Department of Health (TDH) identified a patient colonized with Verona integron-encoded metallo-beta-lactamase-producing carbapenem-resistant Pseudomonas… read more here.
Keywords: integron encoded; vim crpa; crpa; care ... See more keywords
99. Impact of Covid-19, Divergent Genomic Modes of Transmission and Strain Replacement of Carbapenem-Resistant Organisms in a Single Hospital in Singapore over 12 years
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DOI: 10.1093/ofid/ofae631.036
Abstract: Abstract Background Much remains unknown about the different genomic characteristics of transmission comparing Carbapenem-Resistant Enterobacterales (CREs), Carbapenem-Resistant A. baumannii (CRAB) and Carbapenem-Resistant P. aeruginosa (CRPA). In this study, we examine the genomic characteristics and transmission… read more here.
Keywords: transmission; single hospital; crpa; replacement ... See more keywords
484. Metallo-β-Lactamase-Positive Carbapenem-Resistant Enterobacteriaceae and Pseudomonas aeruginosa in the Antibiotic Resistance Laboratory Network, 2017–2018
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DOI: 10.1093/ofid/ofz360.557
Abstract: Abstract Background Infections with metallo-β-lactamase (MBL)-producing organisms are emerging in the United States. Treatment options for these infections are limited. We describe MBL genes among carbapenemase positive carbapenem-resistant Enterobacteriaceae (CP-CRE) and Pseudomonas aeruginosa (CP-CRPA) isolates… read more here.
Keywords: network; mbl; crpa; positive carbapenem ... See more keywords
486. Epidemiology of Carbapenem-Resistant Pseudomonas aeruginosa Identified through the Emerging Infections Program (EIP), United States, 2016–2018
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DOI: 10.1093/ofid/ofz360.559
Abstract: Abstract Background Pseudomonas aeruginosa is intrinsically resistant to many commonly used antimicrobials, and carbapenems are often required to treat infections. We describe the crude incidence, epidemiology, and molecular characteristics of carbapenem-resistant P. aeruginosa (CRPA) in… read more here.
Keywords: crpa; incidence; aeruginosa; carbapenem resistant ... See more keywords
Characterization of carbapenem-resistant Enterobacterales and Pseudomonas aeruginosa carrying multiple carbapenemase genes—Antimicrobial Resistance Laboratory Network, 2018–2022
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DOI: 10.1128/jcm.01220-24
Abstract: ABSTRACT Carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant Pseudomonas aeruginosa (CRPA) are significant public health threats, particularly when harboring carbapenemases. Literature describing the frequencies and phenotypic and genotypic characteristics of isolates harboring multiple carbapenemase genes is limited.… read more here.
Keywords: multiple carbapenemase; carbapenemase; crpa; cre ... See more keywords
Emergence and Expansion of a Carbapenem-Resistant Pseudomonas aeruginosa Clone Are Associated with Plasmid-Borne blaKPC-2 and Virulence-Related Genes
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DOI: 10.1128/msystems.00154-21
Abstract: Health care-associated infections, also known as nosocomial infections, are the most frequent adverse events in health care delivery worldwide, causing high rates of morbidity and mortality and high health care costs. Pseudomonas aeruginosa is one… read more here.
Keywords: crpa; health; blakpc; health care ... See more keywords
Prevalence, Risk Factors, and Molecular Epidemiology of Intestinal Carbapenem-Resistant Pseudomonas aeruginosa
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DOI: 10.1128/spectrum.01344-21
Abstract: Pseudomonas aeruginosa may become multidrug-resistant (MDR) due to multiple inherited and acquired resistance mechanisms. The human gastrointestinal tract is known as a reservoir of P. aeruginosa and its resistance genes. ABSTRACT Pseudomonas aeruginosa may become… read more here.
Keywords: crpa; aeruginosa; risk; resistance ... See more keywords
Combined impact of biosynthesized selenium nanoparticles and imipenem against carbapenem-resistant Pseudomonas aeruginosa and their associated virulence factors
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DOI: 10.1186/s12866-025-03932-6
Abstract: Carbapenem-resistant P. aeruginosa (CRPA) is a significant nosocomial pathogen characterized by extensive antibiotic resistance, representing a serious public health concern. It is regarded as a high-priority target for antibacterial research. This study aimed to isolate… read more here.
Keywords: nps imipenem; crpa; selenium nanoparticles; bap ompa ... See more keywords
blaVIM- and blaOXA-mediated carbapenem resistance among Acinetobacter baumannii and Pseudomonas aeruginosa isolates from the Mulago hospital intensive care unit in Kampala, Uganda
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DOI: 10.1186/s12879-019-4510-5
Abstract: BackgroundBetween January 2015 and July 2017, we investigated the frequency of carbapenem resistant Acinetobacter baumannii (CRAB) and carbapenem resistant Pseudomonas aeruginosa (CRPA) at the Mulago Hospital intensive care unit (ICU) in Kampala, Uganda. Carbapenemase production… read more here.
Keywords: pseudomonas aeruginosa; crab; carbapenemase; crab crpa ... See more keywords
Pediatric Acute Myeloid Leukemia: Unraveling Complexities in Intensive Chemotherapy and the Emergence of Superbugs – A Case Study
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DOI: 10.2147/idr.s478065
Abstract: Background This case report underscores the intricate challenges in managing paediatric patients with acute myeloid leukaemia (AML) undergoing intensive chemotherapy, particularly when complicated by the emergence of multidrug-resistant pathogens such as Carbapenem-Resistant Pseudomonas aeruginosa (CRPA).… read more here.
Keywords: emergence; acute myeloid; crpa; case ... See more keywords
Genomic insights into blaAFM-positive carbapenem-resistant Pseudomonas aeruginosa in China
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DOI: 10.3389/fmicb.2025.1546662
Abstract: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) poses a global threat; however, the epidemiological characteristics and clinical significance of blaAFM-positive CRPA strains in China remain unclear. In this study, continuous surveillance was conducted from 2018 to 2022 in… read more here.
Keywords: positive crpa; carbapenem resistant; blaafm positive; crpa ... See more keywords