Increased serum amyloid A in nasal polyps is associated with systemic corticosteroid insensitivity in patients with chronic rhinosinusitis with nasal polyps: a pilot study
Sign Up to like & getrecommendations! Published in 2017 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-017-4809-z
Abstract: BackgroundSerum amyloid A (SAA) was involved in the pathogenesis of glucocorticoid resistance in lung diseases. However, their association with systemic corticosteroid insensitivity in chronic rhinosinusitis with nasal polyps (CRSwNP) patients remains to be assessed.MethodsThis study… read more here.
Keywords: saa; crswnp patients; corticosteroid insensitivity; nasal polyps ... See more keywords
Predictive Values of Serum IL-33 and sST2 in Endotypes and Postoperative Recurrence of Chronic Rhinosinusitis with Nasal Polyps
Sign Up to like & getrecommendations! Published in 2022 at "Mediators of Inflammation"
DOI: 10.1155/2022/9155080
Abstract: Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disease with high heterogeneity and postoperative recidivation. The IL-33/ST2 axis is known to be involved in Th2 immune responses. This study is aimed at… read more here.
Keywords: sst2; postoperative recurrence; serum sst2; crswnp patients ... See more keywords
Transcriptomics unravels molecular changes associated with cilia and COVID-19 in chronic rhinosinusitis with nasal polyps
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DOI: 10.21203/rs.3.rs-1825032/v1
Abstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common upper respiratory tract complication where the pathogenesis is largely unknown. Herein, we investigated the transcriptome profile in nasal mucosa biopsies of CRSwNP patients and healthy individuals.… read more here.
Keywords: crswnp patients; nasal polyps; polyp mucosa; chronic rhinosinusitis ... See more keywords
Personalized Management of Patients with Chronic Rhinosinusitis with Nasal Polyps in Clinical Practice: A Multidisciplinary Consensus Statement
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12050846
Abstract: Chronic rhinosinusitis (CRS) is a sino-nasal chronic inflammatory disease, occurring in 5–15% of the general population. CRS with nasal polyps (CRSwNP) is present in up to 30% of the CRS population. One-third of CRSwNP patients… read more here.
Keywords: crswnp patients; nasal polyps; management; chronic rhinosinusitis ... See more keywords
Measuring Nasal Patency and the Sense of Smell in CRSwNP Patients Treated with Dupilumab
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DOI: 10.3390/jpm13020234
Abstract: Chronic rhinosinusitis with nasal polyps (CRSwNP) in the most severe forms is associated with a poor quality of life. Dupilumab has been suggested as an add-on treatment option for severe CRSwNP. Severe CRSwNP patients treated… read more here.
Keywords: crswnp patients; treated dupilumab; smell; patients treated ... See more keywords
Local fungus-specific Immunoglobulin E production in chronic rhinosinusitis with nasal polyps.
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DOI: 10.4193/rhin18.225
Abstract: BACKGROUND Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease, and its pathogenesis remains controversial. This study aimed to examine the involvement of fungi in CRSwNP pathogenesis. METHODS We enrolled 29 controls and 111… read more here.
Keywords: nasal polyps; crswnp patients; fungus specific; chronic rhinosinusitis ... See more keywords
Unmet needs in biological treatment of CRS.
Sign Up to like & getrecommendations! Published in 2022 at "Rhinology"
DOI: 10.4193/rhin22.903
Abstract: Endoscopic Sinus Surgery has a 5-year treatment succes (defined as no revision) in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) of 80% and is the most cost effective treatment of chronic rhinosinusitis (CRS). However,… read more here.
Keywords: crswnp patients; smell; biological treatment; crs ... See more keywords