Comparison of Survival Outcomes Among Human Papillomavirus–Negative cT1-2 N1-2b Patients With Oropharyngeal Squamous Cell Cancer Treated With Upfront Surgery vs Definitive Chemoradiation Therapy: An Observational Study
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Oncology"
DOI: 10.1001/jamaoncol.2016.5769
Abstract: Importance Human papillomavirus (HPV)-negative oropharyngeal squamous cell carcinoma (OPSCC) has shown resistance to conventional concurrent chemoradiation (CRT) therapy and carries a relatively poor prognosis in comparison with HPV-positive disease, with decreased locoregional control and overall… read more here.
Keywords: surgery; observational study; ct1; therapy ... See more keywords
Nonpersistent Nanoarchitectures Enhance Concurrent Chemoradiotherapy in an Immunocompetent Orthotopic Model of HPV+ Head/Neck Carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202400949
Abstract: Cisplatin chemoradiotherapy (CRT) is the established standard of care for managing locally advanced human papillomavirus‐positive head/neck carcinoma. The typically young patients may suffer serious and long‐time side effects caused by the treatment, such as dysphagia,… read more here.
Keywords: crt; neck carcinoma; chemoradiotherapy; head neck ... See more keywords
Genomic landscape of locally advanced rectal adenocarcinoma: Comparison between before and after neoadjuvant chemoradiation and effects of genetic biomarkers on clinical outcomes and tumor response.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6169
Abstract: PURPOSE To explore genomic biomarkers in rectal cancer by performing whole-exome sequencing. MATERIALS AND METHODS Pre-chemoradiation (CRT) biopsy and post-CRT surgical specimens were obtained from 27 patients undergoing neoadjuvant CRT followed by definitive resection. Exomes… read more here.
Keywords: clinical outcomes; post crt; genetic biomarkers; crt ... See more keywords
Cardiovascular outcomes after cardiac resynchronization therapy in cardiac amyloidosis.
Sign Up to like & getrecommendations! Published in 2021 at "ESC heart failure"
DOI: 10.1002/ehf2.13663
Abstract: AIMS Cardiac resynchronization therapy (CRT) is highly effective in dilated cardiomyopathy (DCM) patients with impaired left ventricular ejection fraction (LVEF) and left bundle block branch. In cardiac amyloidosis (CA) patients, left ventricular dysfunction and conduction… read more here.
Keywords: response; dcm patients; crt response; resynchronization therapy ... See more keywords
Baseline clinical characteristics of heart failure patients with reduced ejection fraction enrolled in the BUDAPEST‐CRT Upgrade trial
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2609
Abstract: The BUDAPEST‐CRT Upgrade study is the first prospective, randomized, multicentre clinical trial investigating the outcomes after cardiac resynchronization therapy (CRT) upgrade in heart failure (HF) patients with intermittent or permanent right ventricular (RV) pacing with… read more here.
Keywords: crt; heart failure; budapest crt; crt upgrade ... See more keywords
Combined tumor plus nontumor interim FDG‐PET parameters are prognostic for response to chemoradiation in squamous cell esophageal cancer
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.32897
Abstract: We have investigated the prognostic value of two novel interim 18F‐fluorodeoxyglucose positron emission tomography (FDG‐PET) parameters in patients undergoing chemoradiation (CRT) for esophageal squamous cell carcinoma (ESCC): one tumor parameter (maximal standardized uptake ratio rSUR)… read more here.
Keywords: squamous cell; crt; pet parameters; fdg pet ... See more keywords
Prediction of radiation pneumonitis after CRT in patients with advanced NSCLC using multi-region radiomics and attention-based ensemble learning.
Sign Up to like & getrecommendations! Published in 2025 at "Medical physics"
DOI: 10.1002/mp.70140
Abstract: Radiation pneumonitis (RP) is a major dose‐limiting toxicity in concurrent chemoradiotherapy (CRT) for stage III non‐small cell lung cancer (NSCLC). Existing models often analyze a single lung region and rely on a single algorithm, limiting… read more here.
Keywords: radiation; prediction radiation; radiation pneumonitis; crt ... See more keywords
Deep-Penetrating Triple-Responsive Prodrug Nanosensitizer Actuates Efficient Chemoradiotherapy in Pancreatic Ductal Adenocarcinoma Models.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202202834
Abstract: Chemoradiotherapy (CRT) is the most accepted treatment for locally advanced pancreatic ductal adenocarcinoma (PDAC) and can significantly improve the R0 resection rate. However, there are few long-term survivors after CRT. Although some polymer nanoparticles have… read more here.
Keywords: responsive prodrug; chemoradiotherapy; triple responsive; ductal adenocarcinoma ... See more keywords
Improved oncologic outcome with chemoradiotherapy followed by surgery in unresectable intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Strahlentherapie und Onkologie"
DOI: 10.1007/s00066-017-1128-7
Abstract: PurposeTo investigate the ability of chemoradiotherapy (CRT) to down-stage unresectable intrahepatic cholangiocarcinoma (IHCC) to resectable lesions, as well as the factors associated with achieving such down-staging.MethodsThe study cohort comprised 120 patients diagnosed with stage I–IVA IHCC between… read more here.
Keywords: ca19; surgery; eine; der ... See more keywords
The Benefits of Docetaxel Plus Cisplatin and 5-Fluorouracil Induction Therapy in Conversion to Curative Treatment for Locally Advanced Esophageal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Surgery"
DOI: 10.1007/s00268-019-05000-3
Abstract: BackgroundDefinitive chemoradiotherapy (CRT), used for treatment of patients with an initial diagnosis of unresectable locally advanced esophageal cancer, has led to unsatisfactory long-term prognosis. Moreover, CRT can lead to esophageal fistula, perforation, and strictures. Therefore,… read more here.
Keywords: treatment; group; docetaxel plus; advanced esophageal ... See more keywords
Inverse effects of lymph node count on oncological outcomes in rectal cancer based on lymph node positivity status post-neoadjuvant CRT: a large-volume Chinese center experience
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Colorectal Disease"
DOI: 10.1007/s00384-025-04913-x
Abstract: Neoadjuvant chemoradiation therapy (CRT) followed by total mesorectal excision (TME) is the standard of care for locally advanced rectal cancer (LARC). Current guidelines recommend dissecting at least 12 lymph nodes (LNs). However, the impact of… read more here.
Keywords: positivity; rectal cancer; count; lymph node ... See more keywords