CRTC1 Function During Memory Encoding Is Disrupted in Neurodegeneration
Sign Up to like & getrecommendations! Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2016.06.025
Abstract: BACKGROUND Associative memory impairment is an early clinical feature of dementia patients, but the molecular and cellular mechanisms underlying these deficits are largely unknown. In this study, we investigated the functional regulation of the cyclic… read more here.
Keywords: crtc1; neurodegeneration; associative learning; memory deficits ... See more keywords
Gender-specific alteration of energy balance and circadian locomotor activity in the Crtc1 knockout mouse model of depression
Sign Up to like & getrecommendations! Published in 2017 at "Translational Psychiatry"
DOI: 10.1038/s41398-017-0023-4
Abstract: Obesity and depression are major public health concerns, and there is increasing evidence that they share etiological mechanisms. CREB-regulated transcription coactivator 1 (CRTC1) participates in neurobiological pathways involved in both mood and energy balance regulation.… read more here.
Keywords: energy balance; locomotor activity; crtc1;