Ultrasound‐guided plasma rich in growth factors injections and scaffolds hasten motor nerve functional recovery in an ovine model of nerve crush injury
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2079
Abstract: In the present study we evaluated the motor recovery process of peripheral nerve injury (PNI), based on electrophysiological and histomorphometric criteria, after treatment with plasma rich in growth factors (PRGF) injections and scaffolds in an… read more here.
Keywords: crush injury; injections scaffolds; group; ovine model ... See more keywords
Altered Energy Metabolism During Early Optic Nerve Crush Injury: Implications of Warburg-Like Aerobic Glycolysis in Facilitating Retinal Ganglion Cell Survival
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-020-00490-x
Abstract: Neurons, especially axons, are metabolically demanding and energetically vulnerable during injury. However, the exact energy budget alterations that occur early after axon injury and the effects of these changes on neuronal survival remain unknown. Using… read more here.
Keywords: crush injury; nerve crush; optic nerve; injury ... See more keywords
Blockade of ATP P2X7 receptor enhances ischiatic nerve regeneration in mice following a crush injury
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2017.05.025
Abstract: Preventing damage caused by nerve degeneration is a great challenge. There is a growing body of evidence implicating extracellular nucleotides and their P2 receptors in many pathophysiological mechanisms. In this work we aimed to investigate… read more here.
Keywords: crush injury; regeneration; bbg; receptor ... See more keywords
TAK-242 Attenuates Crush Injury Induced Acute Kidney Injury through Inhibiting TLR4/NF-κB Signaling Pathways in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Prehospital and Disaster Medicine"
DOI: 10.1017/s1049023x20001132
Abstract: Abstract Background: To investigate if toll-like receptor (TLR) 4/nuclear factor-kappa B (NF-κB) signaling pathways mediated crush injury induced acute kidney injury (AKI) in rats, and if TAK-242 (a specific inhibitor of TLR4) attenuates the injury… read more here.
Keywords: crush injury; tak 242; signaling pathways; injury ... See more keywords
Therapeutic Effectiveness of Anti-RAGE Antibody Administration in a Rat Model of Crush Injury
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12065-4
Abstract: Crush injury patients often have systemic inflammatory response syndrome that leads to multiple organ failure. Receptor for advanced glycation endproducts (RAGE) functions as a pattern recognition receptor that regulates inflammation. We evaluated the effects of… read more here.
Keywords: crush injury; anti rage; rage; rage antibody ... See more keywords
Time Course of Inflammatory Gene Expression Following Crush Injury in Murine Skeletal Muscle
Sign Up to like & getrecommendations! Published in 2017 at "Nursing Research"
DOI: 10.1097/nnr.0000000000000209
Abstract: Background Early inflammation and secretion of proinflammatory cytokines such as IL-1&bgr;, IL-6, and TNF-&agr; act as the key drivers to regulate inflammation after muscle injury. However, the effects of these key proinflammatory drivers in a… read more here.
Keywords: crush injury; hours fold; muscle; time ... See more keywords
Crush injury with significant soft tissue loss managed utilising biological and dynamic tissue systems: a case study.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of wound care"
DOI: 10.12968/jowc.2023.32.sup2.s17
Abstract: Major traumatic crush injuries are difficult to manage, with high morbidity, requiring prolonged, complex treatment with many procedures. Free-flap reconstruction is often used yet full functionality still may not be regained. In this case study… read more here.
Keywords: case study; crush injury; dynamic tissue; tissue ... See more keywords
Tanshinone IIA attenuates nerve structural and functional damage induced by nerve crush injury in rats
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202532
Abstract: After peripheral nerve crush injury, the fibers of distal nerve segments gradually disintegrate, and axons regrow from the proximal nerve segment, eventually reaching the target organ. However, the axon regeneration is generally not sufficient for… read more here.
Keywords: crush injury; nerve; nerve crush; tanshinone iia ... See more keywords
Knockout of toll-like receptor impairs nerve regeneration after a crush injury
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.20206
Abstract: Background Toll-like receptors (TLRs) are involved in the initiation of Schwann cell activation and subsequent recruitment of macrophages for clearance of degenerated myelin and neuronal debris after nerve injury. The present study was designed to… read more here.
Keywords: crush injury; nerve; injury; nerve regeneration ... See more keywords
Delayed Bone Infarct in the Ilium Following a Pelvic Crush Injury and Embolization: A Case Report
Sign Up to like & getrecommendations! Published in 2017 at "JBJS Case Connector"
DOI: 10.2106/jbjs.cc.16.00151
Abstract: Case: We present a case of delayed osteonecrosis of the ilium. After receiving embolization and multiple orthopaedic procedures following a complex pelvic crush injury, the patient subsequently developed posterior pelvic pain and tenderness over the… read more here.
Keywords: crush injury; pelvic crush; case; embolization ... See more keywords
Evaluation methods of a rat sciatic nerve crush injury model.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2103091
Abstract: BACKGROUND The rat sciatic nerve crush injury model is one of the most commonly used models to research peripheral nerve injury (PNI), however, the evaluation of the model preparation lacks exact standards. This study aimed… read more here.
Keywords: sciatic nerve; crush injury; nerve crush; nerve ... See more keywords