Thresholding of cryo-EM density maps by false discovery rate control
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DOI: 10.1107/s2052252518014434
Abstract: The interpretation of cryo-EM density by atomic models remains a daunting task owing to the identification of appropriate threshold levels at low signal-to-noise ratios in high-resolution shells and weak structural features. It is shown that… read more here.
Keywords: discovery rate; false discovery; cryo density;
Modeling Beta-Traces for Beta-Barrels from Cryo-EM Density Maps
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DOI: 10.1155/2017/1793213
Abstract: Cryo-electron microscopy (cryo-EM) has produced density maps of various resolutions. Although α-helices can be detected from density maps at 5–8 Å resolutions, β-strands are challenging to detect at such density maps due to close-spacing of β-strands.… read more here.
Keywords: cryo density; density maps; density; traces beta ... See more keywords
Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution
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DOI: 10.3390/biom12091290
Abstract: Electron cryo-microscopy (cryo-EM) has emerged as a powerful method by which to obtain three-dimensional (3D) structures of macromolecular complexes at atomic or near-atomic resolution. However, de novo building of atomic models from near-atomic resolution (3–5… read more here.
Keywords: density; building protein; cryo density; density maps ... See more keywords