Super Resolution Cryo-EM Maps with 3D Deep Generative Networks
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2020.11.1801
Abstract: An increasing number of biological macromolecules have been solved with cryo-electron microscopy (cryo-EM). Over the past few years, the resolutions of density maps determined by cryo-EM have largely improved in general. However, there are still… read more here.
Keywords: resolution; super resolution; cryo; resolution cryo ... See more keywords
Electron scattering properties of biological macromolecules and their use for cryo-EM map sharpening
Sign Up to like & getrecommendations! Published in 2022 at "Faraday Discussions"
DOI: 10.1039/d2fd00078d
Abstract: Resolution-dependent loss of contrast in cryo-EM maps may obscure features at high resolution that are critical for map interpretation. Post-processing of cryo-EM maps can improve the interpretability by adjusting the resolution-dependence of structure factor amplitudes… read more here.
Keywords: map; cryo maps; properties biological; scattering properties ... See more keywords
Smart De Novo Macromolecular Structure Modeling from Cryo-EM Maps.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of molecular biology"
DOI: 10.2139/ssrn.4265664
Abstract: The study of macromolecular structures has expanded our understanding of the amazing cell machinery and such knowledge has changed how the pharmaceutical industry develops new vaccines in recent years. Traditionally, x-ray crystallography has been the… read more here.
Keywords: macromolecular structure; smart novo; cryo maps; novo macromolecular ... See more keywords
Bayesian Modeling of Biomolecular Assemblies with Cryo-EM Maps
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2017.00015
Abstract: A growing array of experimental techniques allows us to characterize the three-dimensional structure of large biological assemblies at increasingly higher resolution. In addition to X-ray crystallography and nuclear magnetic resonance in solution, new structure determination… read more here.
Keywords: modeling biomolecular; cryo maps; bayesian modeling; structure ... See more keywords
MarkovFit: Structure Fitting for Protein Complexes in Electron Microscopy Maps Using Markov Random Field
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.935411
Abstract: An increasing number of protein complex structures are determined by cryo-electron microscopy (cryo-EM). When individual protein structures have been determined and are available, an important task in structure modeling is to fit the individual structures… read more here.
Keywords: cryo maps; electron microscopy; microscopy; using markov ... See more keywords