Cryo‐EM structure of the MinCD copolymeric filament from Pseudomonas aeruginosa at 3.1 Å resolution
Sign Up to like & getrecommendations! Published in 2019 at "Febs Letters"
DOI: 10.1002/1873-3468.13471
Abstract: Positioning of the division site in many bacterial species relies on the MinCDE system, which prevents the cytokinetic Z‐ring from assembling anywhere but the mid‐cell, through an oscillatory diffusion‐reaction mechanism. MinD dimers bind to membranes… read more here.
Keywords: resolution; pseudomonas aeruginosa; cryo structure; mincd ... See more keywords
Cryo-EM structure reveals cylindrical nucleocapsids from two polydnaviruses
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Virology"
DOI: 10.1007/s00705-018-3958-8
Abstract: Bracovirus is one of the two polydnavirus genera. Here, we used a cryo-EM analysis to reveal the near-native morphology of two nucleocapsid-containing model bracoviruses: Microplitis bicoloratus bracovirus (MbBV) and Microplitis mediator bracovirus (MmBV). MbBV and… read more here.
Keywords: structure reveals; cryo structure; structure; cylindrical nucleocapsids ... See more keywords
Cryo-EM structure of human ABCB8 transporter in nucleotide binding state.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.04.007
Abstract: Human ATP-binding cassette transporter 8 of subfamily B (hABCB8) is an ABC transporter that located in the inner membrane of mitochondria. The ABCB8 is involved in the maturation of Fe-S and protects the heart from… read more here.
Keywords: structure human; cryo structure; human abcb8; transporter ... See more keywords
Cryo-Em Structure of the Plasmodium Proteasome in the Search of New Antimalarials
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.1785
Abstract: The Plasmodium falciparum proteasome has been suggested as possible target for new generation antimalarials. However, the proteasome is essential in all eukaryotes and a proteasome inhibitor with potential to be developed as antimalarial must specifically… read more here.
Keywords: cryo structure; plasmodium proteasome; structure; plasmodium ... See more keywords
Cryo-EM Structure Determination and Model Fitting of the Proton-Gated Ligand-Gated Ion Channel glic at Multiple pH States
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2019.11.3155
Abstract: Cryo-EM Structure Determination and Model Fitting of the Proton-Gated Ligand-Gated Ion Channel glic at Multiple pH States read more here.
Keywords: cryo structure; determination model; fitting proton; structure determination ... See more keywords
Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.04.010
Abstract: Summary Relaxases play essential roles in conjugation, the main process by which bacteria exchange genetic material, notably antibiotic resistance genes. They are bifunctional enzymes containing a trans-esterase activity, which is responsible for nicking the DNA… read more here.
Keywords: conjugation; molecular basis; cryo structure; dna ... See more keywords
Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.03.080
Abstract: Human Dicer (hDicer) is a multi-domain protein belonging to the RNase III family. It plays pivotal roles in small RNA biogenesis during the RNA interference (RNAi) pathway by processing a diverse range of double-stranded RNA (dsRNA)… read more here.
Keywords: human dicer; pre mirna; cryo structure; hdicer ... See more keywords
Cryo-EM structure of full-length HIV-1 Env bound with the Fab of antibody PG16.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.11.028
Abstract: The HIV-1 envelope protein (Env) is the target of neutralizing antibodies and the template for vaccine immunogen design. The dynamic conformational equilibrium of trimeric Env influences its antigenicity and potential immunogenicity. Antibodies that bind at… read more here.
Keywords: cryo structure; hiv; fab; structure ... See more keywords
Cryo-EM Structure of a Bacterial Lipid Transporter YebT.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.12.008
Abstract: The outer membrane (OM) of gram negative bacteria is asymmetric, with LPS on the outer surface and phospholipids (PLs) on the inner surface. This unique organization of OM makes gram negative bacteria resistant to many… read more here.
Keywords: yebt; lipid transporter; cryo structure; structure ... See more keywords
Cryo-EM structure of native spherical subviral particles isolated from HBV carriers.
Sign Up to like & getrecommendations! Published in 2019 at "Virus research"
DOI: 10.1016/j.virusres.2018.10.015
Abstract: Hepatitis B virus (HBV) contains 3 types of particles, i.e., 22-nm-diameter spherical and tubular subviral particles (SVPs) and 44-nm-diameter Dane particles. The SVPs are non-infectious and present strong immunogenicity, while Dane particles are infectious. In… read more here.
Keywords: cryo structure; hbv; subviral particles; native spherical ... See more keywords
Cryo-EM Structure of the Novel Viral Chaperonin, Encoded by Gene 228 of Bacteriophage AR9 Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2020 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927620017584
Abstract: Chaperonins are some of the most studied families of chaperones. They are multimeric complexes that ensure the proper folding of newly synthesized polypeptide chains and prevent the aggregation of denatured stressed proteins in an ATP-dependent… read more here.
Keywords: structure novel; novel viral; cryo structure; bacteriophage ... See more keywords