The 3.5-Å CryoEM Structure of Nanodisc-Reconstituted Yeast Vacuolar ATPase Vo Proton Channel.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.02.006
Abstract: The molecular mechanism of transmembrane proton translocation in rotary motor ATPases is not fully understood. Here, we report the 3.5-Å resolution cryoEM structure of the lipid nanodisc-reconstituted Vo proton channel of the yeast vacuolar H+-ATPase,… read more here.
Keywords: proton channel; cryoem structure; nanodisc reconstituted; proton ... See more keywords
CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing
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DOI: 10.1038/s41467-017-01241-9
Abstract: U1 snRNP plays a critical role in 5ʹ-splice site recognition and is a frequent target of alternative splicing factors. These factors transiently associate with human U1 snRNP and are not amenable for structural studies, while… read more here.
Keywords: saccharomyces cerevisiae; cryoem structure; snrnp; yeast snrnp ... See more keywords
CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction
Sign Up to like & getrecommendations! Published in 2017 at "Science Advances"
DOI: 10.1126/sciadv.1701264
Abstract: CryoEM structure of MxB tubes at 4.6 Å resolution reveals novel interfaces responsible for assembly and anti–HIV-1 activity. Human dynamin–like, interferon-induced myxovirus resistance 2 (Mx2 or MxB) is a potent HIV-1 inhibitor. Antiviral activity requires… read more here.
Keywords: cryoem structure; mxb; reveals novel; hiv ... See more keywords
The cryoEM structure of cytochrome bd from C. glutamicum provides novel insights into structural properties of actinobacterial terminal oxidases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.1085463
Abstract: Cytochromes bd are essential for microaerobic respiration of many prokaryotes including a number of human pathogens. These enzymes catalyze the reduction of molecular oxygen to water using quinols as electron donors. Their importance for prokaryotic… read more here.
Keywords: structure; cryoem structure; structure cytochrome; glutamicum provides ... See more keywords