CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation
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DOI: 10.1038/s41467-019-11759-9
Abstract: Transcription by RNA polymerase V (Pol V) in plants is required for RNA-directed DNA methylation, leading to transcriptional gene silencing. Global chromatin association of Pol V requires components of the DDR complex DRD1, DMS3 and… read more here.
Keywords: cryoem structures; dms3; dna methylation; rna directed ... See more keywords
CryoEM structures of open dimers of Gyrase A in complex with DNA illuminate mechanism of strand passage.
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DOI: 10.2210/pdb6n1q/pdb
Abstract: Gyrase is a unique type IIA topoisomerase that uses ATP hydrolysis to maintain the negatively supercoiled state of bacterial DNA. In order to perform its function, gyrase undergoes a sequence of conformational changes that consist… read more here.
Keywords: cryoem structures; gyrase; strand passage; dna ... See more keywords