Safety and efficacy of cryopreserved platelets in bleeding thrombocytopenic patients
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DOI: 10.1111/trf.14946
Abstract: Activity Disclosures No commercial support has been accepted related to the development or publication of this activity. CME Editor, Anne F. Eder, MD, PhD reported no conflicts of interest or financial relationships relevant to this… read more here.
Keywords: safety efficacy; efficacy cryopreserved; conflicts interest; interest ... See more keywords
The use of cryopreserved platelets in the treatment of polytraumatic patients and patients with massive bleeding
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DOI: 10.1111/trf.15177
Abstract: The short shelf‐life of fresh platelets limits their efficient inventory management and availability during a massive transfusion protocol. Risk of insufficient availability can be mitigated by building an inventory of cryopreserved platelets (CPs). read more here.
Keywords: patients patients; use cryopreserved; polytraumatic patients; cryopreserved platelets ... See more keywords
The use of cryopreserved platelets in a trauma‐induced hemorrhage model
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DOI: 10.1111/trf.15937
Abstract: Cryopreserved platelet products can be stored for years and are mainly used in military settings. Following thawing, cryopreserved platelets are activated, resulting in faster clot formation but reduced aggregation in vitro, rendering their efficacy in… read more here.
Keywords: induced hemorrhage; use cryopreserved; platelets trauma; hemorrhage ... See more keywords
Cryopreserved platelets and their suitability in being re‐suspended in additive solution
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DOI: 10.1111/vox.12993
Abstract: Cryopreserved platelets are generally produced and stored in plasma. With the advent of additive solutions being routinely used it would be prudent to examine producing and storing these units in a platelet additive solution (SSP+). read more here.
Keywords: suspended additive; additive solution; platelets suitability; suitability suspended ... See more keywords
Off-the-shelf cryopreserved platelets for the detection of HIT and VITT antibodies.
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DOI: 10.1182/blood.2022017283
Abstract: Heparin-induced thrombocytopenia (HIT) is suspected much more often than it is confirmed. Technically-simple Platelet Factor-4 (PF4)-polyanion enzyme-linked immunosorbent assays (ELISAs) are sensitive but non-specific. In contrast, accurate functional tests such as the serotonin release assay,… read more here.
Keywords: hit vitt; heparin; vitt antibodies; release ... See more keywords