Cryptic Oxidative Transamination of Hydroxynaphthoquinone in Natural Product Biosynthesis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c13074
Abstract: Pyridoxal 5'-phosphate (PLP)-dependent enzymes are a group of versatile enzymes that catalyze various reactions, but only a small number of them react with O2. Here, we report an unprecedented PLP-dependent enzyme, NphE, that catalyzes both… read more here.
Keywords: transamination; biosynthesis; cryptic oxidative; transamination hydroxynaphthoquinone ... See more keywords
Biosynthesis of the allelopathic alkaloid gramine in barley by a cryptic oxidative rearrangement
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DOI: 10.1126/science.adk6112
Abstract: The defensive alkaloid gramine not only protects barley and other grasses from insects but also negatively affects their palatability to ruminants. The key gene for gramine formation has remained elusive, hampering breeding initiatives. In this… read more here.
Keywords: barley; oxidative rearrangement; cryptic oxidative; gramine ... See more keywords