A comparative metabologenomic approach reveals mechanistic insights into Streptomyces antibiotic crypticity
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DOI: 10.1073/pnas.2103515118
Abstract: Significance Streptomyces genomes harbor a trove of biosynthetic gene clusters (BGCs) that encode for drug-like molecules. However, only a fraction of these readily yield expected products. To investigate why this is, we used polycyclic tetramate… read more here.
Keywords: production; ptm producers; antibiotic crypticity; approach ... See more keywords