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Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.06.016
Abstract: Diagnosis of central nervous system cryptococcosis relies on a spectrum of methods but has improved with lateral flow diagnostic assays that detect capsular polysaccharide antigens of Cryptococcus. Here, we present the case of an HIV-infected… read more here.
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Published in 2024 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2024.2369243
Abstract: ABSTRACT Background Cryptococcosis is a global invasive mycosis associated with significant morbidity and mortality. Cryptococcal antigen (CrAg) testing from serum and cerebrospinal fluid (CSF) has been regarded as a gold standard for early diagnosis. This… read more here.
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Published in 2020 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2020.1785871
Abstract: ABSTRACT Introduction Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis. Development of highly sensitive… read more here.
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Published in 2024 at "Medical mycology"
DOI: 10.1093/mmy/myae093
Abstract: Several false positive low serum cryptococcal antigen (SCrAg) reports by lateral flow assay (LFA) were identified in late 2016 at our tertiary care hospital. After the recall and correction of the problem in the reagent,… read more here.
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Published in 2018 at "Medical mycology"
DOI: 10.1093/mmy/myx092
Abstract: Cryptococcal antigen (CryAg) testing in serum and CSF is a clue diagnostic tool for cryptococcosis. In this study, we reviewed the performances of the CryAg detection (Premier EIA, Meridian) routinely performed in broncho-alveolar lavage fluid… read more here.
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Published in 2025 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofae631.2293
Abstract: Abstract Background In the fall of 2016, a cluster of low positive serum cryptococcal antigen titers (SCrAg) ≤ 1:20 was traced back to a manufacturing defect. Subsequently, SCrAg ≤ 1:10 were reported with a disclaimer… read more here.
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Published in 2020 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.02307-20
Abstract: High cryptococcal antigen (CrAg) titers in blood are associated with subclinical meningitis and mortality in CrAg-positive individuals with advanced HIV disease (AHD). We evaluated a novel semiquantitative lateral flow assay (LFA), CryptoPS, that may be… read more here.
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-054057
Abstract: Introduction Cryptococcal meningitis is a common fungal opportunistic infection and a leading cause of death among people with advanced HIV disease in sub-Saharan Africa. The WHO recommends cryptococcal antigen (CrAg) screening followed by pre-emptive therapy… read more here.
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Published in 2022 at "Iranian Journal of Microbiology"
DOI: 10.18502/ijm.v14i5.10970
Abstract: Background and Objectives: Cryptococcosis is an opportunistic mycosis, caused by Cryptococcus neoformans. Cryptococcal meningitis is one of the most fatal opportunistic infections associated with human immunodeficiency virus (HIV) infection. The aim of this study was… read more here.
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Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.00409
Abstract: Background: Cryptococcal meningitis (CM) is a major cause of AIDS-related mortality in Africa. Detection of serum cryptococcal antigen (CrAg) predicts development of CM in antiretroviral (ART) naïve HIV-infected patients with severe immune depression. Systematic pre-ART… read more here.
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Published in 2018 at "Indian Journal of Medical Microbiology"
DOI: 10.4103/ijmm.ijmm_18_164
Abstract: Cryptococcus gattii predominantly causes central nervous system and pulmonary infection in both immunocompromised and immunocompetent patients with substantial morbidity. We report a case of rapidly fatal meningitis by C. gattii in an HIV–non-infected man with… read more here.