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Published in 2017 at "Infection"
DOI: 10.1007/s15010-017-1059-3
Abstract: PurposeCryptococcal meningitis is a potentially fatal fungal infection associated with a significant attributable morbidity and mortality, especially among HIV/AIDS patients. The first-line therapy for the treatment of this clinical entity is the combinatory therapy of…
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Keywords:
meningitis;
hiv patients;
meningitis hiv;
treatment ... See more keywords
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Published in 2019 at "CNS Spectrums"
DOI: 10.1017/s1092852919000233
Abstract: Abstract Introduction Cryptococcal Meningitis is a fungal infectious disease of worldwide distribution, primarily associated with underlying immunosuppression conditions such as HIV infection, glucocorticoid treatment, status post organ transplantation and oncological treatments. Prevalence is particularly high…
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Keywords:
case study;
immunocompetent patients;
meningitis;
cryptococcal meningitis ... See more keywords
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Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01598
Abstract: Clinical treatment of cryptococcal meningitis (CM) remains a significant challenge because of the lack of effective and safe drug therapies. Developing novel CM therapeutic agents with novel chemical scaffolds and new modes of action is…
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Keywords:
treatment cryptococcal;
discovery carboline;
compound;
cryptococcal meningitis ... See more keywords
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Published in 2020 at "Journal of Neurosciences in Rural Practice"
DOI: 10.1055/s-0039-3402895
Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune and multisystem disorder, which frequently affects young women. During pregnancy, SLE flares could occur up to 65%, with renal and hematological manifestations being the most common. However,…
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Keywords:
lupus;
pregnant woman;
cerebral lupus;
cryptococcal meningitis ... See more keywords
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Published in 2022 at "Critical reviews in microbiology"
DOI: 10.1080/1040841x.2022.2159786
Abstract: Cryptococcal meningitis (CM) is an invasive fungal disease that currently poses a threat to human health worldwide, with high morbidity and mortality, particularly in immunocompromised patients. Although CM mainly occurs in HIV-positive patients and other…
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Keywords:
cryptococcal meningitis;
apparently immunocompetent;
meningitis apparently;
microbiology ... See more keywords
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Published in 2020 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2020.1785871
Abstract: ABSTRACT Introduction Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis. Development of highly sensitive…
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Keywords:
meningitis;
cryptococcal antigen;
screening programs;
cryptococcal meningitis ... See more keywords
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Published in 2021 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2020.0202
Abstract: BACKGROUND Early ART initiation after cryptococcal meningitis increases mortality, and those unmasking cryptococcosis after =4 doses/week or moderate adherence. With lamivudine, 72% (18/22) had detectable levels consistent with adherence over the last 3 days prior…
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Keywords:
art;
adherence;
dried blood;
cryptococcal meningitis ... See more keywords
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Published in 2023 at "Medical mycology"
DOI: 10.1093/mmy/myad040
Abstract: Oxidative imbalances have been observed in various neurological diseases. Despite the microbiological control in cryptococcal meningitis (CM), a proportion of previously healthy patients experience a clinical deterioration known as post-infectious inflammatory response syndrome (PIIRS). However,…
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Keywords:
cryptococcal meningitis;
infectious inflammatory;
post infectious;
inflammatory response ... See more keywords
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Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac416
Abstract: Abstract Background Increased intracranial pressure (ICP) frequently complicates cryptococcal meningitis. Therapeutic lumbar punctures (LPs) have acute survival benefits in the first week, and we sought to understand the longer-term survival impact of therapeutic LPs. Methods…
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Keywords:
cryptococcal meningitis;
icp;
baseline icp;
lumbar punctures ... See more keywords
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Published in 2023 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofad156
Abstract: Abstract Among persons with human immunodeficiency virus–associated cryptococcal meningitis serum hyponatremia is a risk factor for mortality; however, the role of hyponatremia in persons with asymptomatic cryptococcal antigenemia is unknown. We found that serum hyponatremia…
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Keywords:
cryptococcal meningitis;
hyponatremia;
meningitis death;
cryptococcal antigenemia ... See more keywords
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Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx127
Abstract: Summary Acute kidney injury (AKI) occurs commonly in human immunodeficiency virus–infected patients with cryptococcal meningitis treated with 2 weeks of amphotericin B deoxycholate and is associated with mortality. Urine protein may play a role in…
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Keywords:
kidney injury;
human immunodeficiency;
cryptococcal meningitis;
acute kidney ... See more keywords