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   Articles with "cryptococcal meningitis" as a keyword



Clinical evaluation of the antifungal effect of sertraline in the treatment of cryptococcal meningitis in HIV patients: a single Mexican center experience

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recommendations! Published in 2017 at "Infection"

DOI: 10.1007/s15010-017-1059-3

Abstract: PurposeCryptococcal meningitis is a potentially fatal fungal infection associated with a significant attributable morbidity and mortality, especially among HIV/AIDS patients. The first-line therapy for the treatment of this clinical entity is the combinatory therapy of… read more here.

Keywords: meningitis; hiv patients; meningitis hiv; treatment ... See more keywords

29 Cryptococcal Meningitis Leading to Fatal Outcomes in Immunocompetent Patients: A Case Study and Review of Literature

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recommendations! Published in 2019 at "CNS Spectrums"

DOI: 10.1017/s1092852919000233

Abstract: Abstract Introduction Cryptococcal Meningitis is a fungal infectious disease of worldwide distribution, primarily associated with underlying immunosuppression conditions such as HIV infection, glucocorticoid treatment, status post organ transplantation and oncological treatments. Prevalence is particularly high… read more here.

Keywords: case study; immunocompetent patients; meningitis; cryptococcal meningitis ... See more keywords

Discovery of Carboline Derivatives as Potent Antifungal Agents for the Treatment of Cryptococcal Meningitis.

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recommendations! Published in 2019 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.8b01598

Abstract: Clinical treatment of cryptococcal meningitis (CM) remains a significant challenge because of the lack of effective and safe drug therapies. Developing novel CM therapeutic agents with novel chemical scaffolds and new modes of action is… read more here.

Keywords: treatment cryptococcal; discovery carboline; compound; cryptococcal meningitis ... See more keywords

Brain-infiltrating CD4 T cells drive inflammatory microglia proliferation during cryptococcal meningitis in mice

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-64034-5

Abstract: Cryptococcal meningitis is a fungal infection in patients with compromised CD4 T cell function. CD4 T cells provide killing signals to macrophages, principally IFNγ, to limit intracellular fungal replication. However, CD4 T cells may also… read more here.

Keywords: cd4 cell; brain; cd4 cells; cryptococcal meningitis ... See more keywords

Cerebral Lupus and Cryptococcal Meningitis in a Pregnant Woman

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recommendations! Published in 2020 at "Journal of Neurosciences in Rural Practice"

DOI: 10.1055/s-0039-3402895

Abstract: Systemic lupus erythematosus (SLE) is a chronic autoimmune and multisystem disorder, which frequently affects young women. During pregnancy, SLE flares could occur up to 65%, with renal and hematological manifestations being the most common. However,… read more here.

Keywords: lupus; pregnant woman; cerebral lupus; cryptococcal meningitis ... See more keywords

Cryptococcal meningitis in apparently immunocompetent patients.

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recommendations! Published in 2022 at "Critical reviews in microbiology"

DOI: 10.1080/1040841x.2022.2159786

Abstract: Cryptococcal meningitis (CM) is an invasive fungal disease that currently poses a threat to human health worldwide, with high morbidity and mortality, particularly in immunocompromised patients. Although CM mainly occurs in HIV-positive patients and other… read more here.

Keywords: cryptococcal meningitis; apparently immunocompetent; meningitis apparently; microbiology ... See more keywords
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Cryptococcal meningitis: a review of cryptococcal antigen screening programs in Africa

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recommendations! Published in 2020 at "Expert Review of Anti-infective Therapy"

DOI: 10.1080/14787210.2020.1785871

Abstract: ABSTRACT Introduction Cryptococcal meningitis remains a significant contributor to AIDS-related mortality despite widened access to antiretroviral therapy. Cryptococcal antigen (CrAg) can be detected in the blood prior to development of meningitis. Development of highly sensitive… read more here.

Keywords: meningitis; cryptococcal antigen; screening programs; cryptococcal meningitis ... See more keywords

A Descriptive Analysis of Dried Blood Spot Adherence Testing Among Ugandans with HIV Presenting with Cryptococcal Meningitis.

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recommendations! Published in 2021 at "AIDS research and human retroviruses"

DOI: 10.1089/aid.2020.0202

Abstract: BACKGROUND Early ART initiation after cryptococcal meningitis increases mortality, and those unmasking cryptococcosis after =4 doses/week or moderate adherence. With lamivudine, 72% (18/22) had detectable levels consistent with adherence over the last 3 days prior… read more here.

Keywords: art; adherence; dried blood; cryptococcal meningitis ... See more keywords

The effect of serum uric acid, bilirubin and albumin levels on antioxidant status in HIV-negative immunocompetent cryptococcal meningitis patients with post-infectious inflammatory response syndrome.

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recommendations! Published in 2023 at "Medical mycology"

DOI: 10.1093/mmy/myad040

Abstract: Oxidative imbalances have been observed in various neurological diseases. Despite the microbiological control in cryptococcal meningitis (CM), a proportion of previously healthy patients experience a clinical deterioration known as post-infectious inflammatory response syndrome (PIIRS). However,… read more here.

Keywords: cryptococcal meningitis; infectious inflammatory; post infectious; inflammatory response ... See more keywords

Deciphering Prognostic Indicators in Non-HIV Cryptococcal Meningitis: Constructing and Validating a Predictive Nomogram Model.

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recommendations! Published in 2024 at "Medical mycology"

DOI: 10.1093/mmy/myae092

Abstract: Cryptococcal meningitis (CM) is a well-recognized fungal infection, with substantial mortality in HIV-infected individuals. However, the incidence, risk factors, and outcomes in non-HIV adults remain poorly understood. This study aims to investigate the characteristics and… read more here.

Keywords: cryptococcal meningitis; prognostic indicators; model; indicators non ... See more keywords

Therapeutic Lumbar Punctures in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis: Should Opening Pressure Direct Management?

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recommendations! Published in 2022 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofac416

Abstract: Abstract Background Increased intracranial pressure (ICP) frequently complicates cryptococcal meningitis. Therapeutic lumbar punctures (LPs) have acute survival benefits in the first week, and we sought to understand the longer-term survival impact of therapeutic LPs. Methods… read more here.

Keywords: cryptococcal meningitis; icp; baseline icp; lumbar punctures ... See more keywords