Cryptotanshinone protects dextran sulfate sodium‐induced experimental ulcerative colitis in mice by inhibiting intestinal inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6693
Abstract: The incidence of ulcerative colitis (UC) is increasing in recent years. The protective effect of cryptotanshinone, a natural compound from Salvia miltiorrhiza Bunge, on UC was investigated both in vivo and in vitro models. UC… read more here.
Keywords: dextran sulfate; sulfate sodium; intestinal inflammation; cryptotanshinone ... See more keywords
Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2017.04.026
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Cryptotanshinone, a natural compound isolated from the roots of Salvia miltiorrhiza Bge. (Danshen), is a commonly used traditional Chinese medicine to treat high blood pressure in some countries. It has been shown that… read more here.
Keywords: cryptotanshinone; miltiorrhiza bge; ovarian cancer; cancer cells ... See more keywords
A novel topoisomerase 2a inhibitor, cryptotanshinone, suppresses the growth of PC3 cells without apparent cytotoxicity
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.07.007
Abstract: ABSTRACT DNA topoisomerase 2, which is ubiquitously expressed in eukaryotic cells, is an essential nuclear enzyme that promotes cell survival by regulating DNA topology and chromatid separation. This enzyme has been validated as a target… read more here.
Keywords: topoisomerase inhibitor; novel topoisomerase; cryptotanshinone; topoisomerase ... See more keywords
Co-Assembled Cryptotanshinone Derivative and Glycyrrhizic Acid Carrier-Free Hydrogel: A Synergistic Approach to Acne Treatment.
Sign Up to like & getrecommendations! Published in 2025 at "Nano letters"
DOI: 10.1021/acs.nanolett.4c05420
Abstract: Traditional anti-inflammatory and antimicrobial drugs often fail to address all aspects of acne vulgaris and are prone to causing adverse effects such as skin irritation, dryness, and allergic reactions. Consequently, there is a growing preference… read more here.
Keywords: treatment; glycyrrhizic acid; hydrogel; acne treatment ... See more keywords
Cryptotanshinone enhances wound healing in type 2 diabetes with modulatory effects on inflammation, angiogenesis and extracellular matrix remodelling
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2020.1803369
Abstract: Abstract Context Cryptotanshinone (CT) is a diterpene quinone compound from Salvia miltiorrhiza Bge. Labiatae has been widely used in cardio-cerebral vascular diseases, which could be potentially effective in treating diabetic wounds. Objective This study evaluates… read more here.
Keywords: wound healing; vegf; extracellular matrix; cryptotanshinone ... See more keywords
The Role of Cryptotanshinone Regulates HTR‐8/SVneo Cells Activity Through the p53/STAT3 Pathway in Unexplained Recurrent Spontaneous Abortion
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.70163
Abstract: This study sought to investigate the therapeutic effects and mechanisms of cryptotanshinone (CT) on unexplained recurrent spontaneous abortion (URSA). read more here.
Keywords: spontaneous abortion; recurrent spontaneous; cryptotanshinone; unexplained recurrent ... See more keywords
Cryptotanshinone From Salvia miltiorrhiza Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model
Sign Up to like & getrecommendations! Published in 2022 at "Natural Product Communications"
DOI: 10.1177/1934578x221130874
Abstract: Cryptotanshinone is a quinone diterpene extracted from the traditional Chinese medicine Salvia miltiorrhiza root that shows obvious anticancer activity. The aim of this study was to investigate the mechanism of action of cryptotanshinone as an… read more here.
Keywords: salvia miltiorrhiza; cryptotanshinone; gastric cancer; model ... See more keywords
Cryptotanshinone Attenuates Oxygen-Glucose Deprivation/ Recovery-Induced Injury in an in vitro Model of Neurovascular Unit
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2019.00381
Abstract: Cryptotanshinone (CTs), an active component isolated from the root of Salvia miltiorrhiza (SM), has been shown to exert potent neuroprotective property. We here established an oxygen-glucose deprivation/recovery (OGD/R)-injured Neurovascular Unit (NVU) model in vitro to… read more here.
Keywords: glucose deprivation; deprivation recovery; cryptotanshinone; oxygen glucose ... See more keywords
Comparative Proteomics Analysis Reveals the Reversal Effect of Cryptotanshinone on Gefitinib-Resistant Cells in Epidermal Growth Factor Receptor-Mutant Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.837055
Abstract: Cryptotanshinone (CTS) is a lipophilic constituent of Salvia miltiorrhiza, with a broad-spectrum anticancer activity. We have observed that CTS enhances the efficacy of gefitinib in human lung cancer H1975 cells, yet little is known about… read more here.
Keywords: lung cancer; h1975 cells; cryptotanshinone; differential proteins ... See more keywords
Anticancer potential of cryptotanshinone on breast cancer treatment; A narrative review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.979634
Abstract: Breast cancer has recently been known as the first lethal malignancy in women worldwide. Despite the existing treatments that have improved the patients’ prognosis, some types of breast cancer are serious challenges to treat. Therefore,… read more here.
Keywords: cryptotanshinone; breast cancer; cancer treatment; cancer ... See more keywords
Preparation and optimization of surface stabilized cryptotanshinone nanocrystals with enhanced bioavailability
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1122071
Abstract: Cryptotanshinone (CTS) is a plant product extracted from Salvia miltiorrhiza Bunge with various pharmacological significances. In addition to its activities against coronary heart disease, hyperlipidemia, stroke, hepatitis and chronic renal failure, it demonstrates antimetastatic effects.… read more here.
Keywords: surface stabilized; bioavailability; cryptotanshinone; optimization surface ... See more keywords