Vibrational spectroscopic and Hirshfeld surface analysis of carvedilol crystal forms
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.10.051
Abstract: &NA; The drug carvedilol, used to treat cardiovascular conditions, is known to exist in distinct crystalline forms. Polymorphs II and III and the hydrate are characterized by variations in their molecular packing and conformation. This… read more here.
Keywords: hirshfeld surface; surface; spectroscopic; carvedilol ... See more keywords
Structures of two novel crystal forms of Aspergillus oryzae alpha amylase (taka-amylase).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2021.02.008
Abstract: The structures of Aspergillus oryzae α-amylase were determined in a tetragonal crystal, having one molecule as asymmetric unit, and a monoclinic crystal with two molecules as asymmetric unit. Both crystal forms were obtained from trace… read more here.
Keywords: tetragonal crystal; amylase; asymmetric unit; crystal ... See more keywords
New crystal forms of the integral membrane Escherichia coli quinol:fumarate reductase suggest that ligands control domain movement.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2017.11.004
Abstract: Quinol:fumarate reductase (QFR) is an integral membrane protein and a member of the respiratory Complex II superfamily. Although the structure of Escherichia coli QFR was first reported almost twenty years ago, many open questions of… read more here.
Keywords: integral membrane; coli; fumarate reductase; crystal forms ... See more keywords
Crystal Forms and Microphase Structures of Poly(vinylidene fluoride-co-hexafluoropropylene) Physically and Chemically Incorporated with Ionic Liquids
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecules"
DOI: 10.1021/acs.macromol.8b02087
Abstract: The effects of incorporating two imidazolium-type ionic liquids (ILs), 1-vinyl-3-butylimidazolium bis(trifluoromethylsulfonyl)imide (IL-TFSI) and 1-vinyl-3-butylimidazolium chloride (IL-Cl), on the crystal forms and phase microstructures of poly(vinylidene fluoride-co-hexafluoropropylene), P(VDF-co-HFP), were investigated. No change in the crystal form… read more here.
Keywords: poly vinylidene; vinylidene fluoride; fluoride hexafluoropropylene; hfp ... See more keywords
Crystal Forms of the Antihypertensive Drug Irbesartan: A Crystallographic, Spectroscopic, and Hirshfeld Surface Analysis Investigation
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c00545
Abstract: The design of new pharmaceutical solids with improved physical and chemical properties can be reached through in-detail knowledge of the noncovalent intermolecular interactions between the molecules in the context of crystal packing. Although crystallization from… read more here.
Keywords: compound; antihypertensive drug; analysis; forms antihypertensive ... See more keywords
Prepared MnO2 with different crystal forms as electrode materials for supercapacitors: experimental research from hydrothermal crystallization process to electrochemical performances
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra06369e
Abstract: The aim of this study was to prepare manganese dioxide with different crystal forms through hydrothermal treatment of MnSO4·H2O–KMnO4 precursors at various precursor ratios, temperatures, time periods, and pH values. The effect of the preparation… read more here.
Keywords: crystallization; different crystal; crystal; crystal form ... See more keywords
On the crystal forms of NDI-C6: annealing and deposition procedures to access elusive polymorphs.
Sign Up to like & getrecommendations! Published in 2022 at "Faraday discussions"
DOI: 10.1039/d1fd00100k
Abstract: NDI-C6 has been extensively studied for its semiconducting properties and its processability. It is known to have several polymorphs and a high thermal expansion. Here we report the full thermal characterization of NDI-C6 by combining… read more here.
Keywords: form; thermal expansion; deposition; form form ... See more keywords
A new crystal form of the NSAID dexketoprofen.
Sign Up to like & getrecommendations! Published in 2019 at "Acta crystallographica. Section C, Structural chemistry"
DOI: 10.1107/s2053229619006533
Abstract: Dexketoprofen [(2S)-2-(3-benzoylphenyl)propanoic acid], C16H14O3, is the S-enantiomer of ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, antipyretic and anti-inflammatory properties, and finds applications for the short-term treatment of mild to moderate pain. A new… read more here.
Keywords: dxkp; crystal form; dexketoprofen; new crystal ... See more keywords
The Relevance of Crystal Forms in the Pharmaceutical Field: Sword of Damocles or Innovation Tools?
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169013
Abstract: This review is aimed to provide to an “educated but non-expert” readership and an overview of the scientific, commercial, and ethical importance of investigating the crystalline forms (polymorphs, hydrates, and co-crystals) of active pharmaceutical ingredients… read more here.
Keywords: crystal; innovation; pharmaceutical field; forms pharmaceutical ... See more keywords
Two Crystal Forms of a Hydrated 2:1 β-Cyclodextrin Fluconazole Complex: Single Crystal X-ray Structures, Dehydration Profiles, and Conditions for Their Individual Isolation
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26154427
Abstract: Inclusion complexes between cyclodextrins (CDs) and active pharmaceutical ingredients (APIs) have potential for pharmaceutical formulation. Since crystallization of a given complex may result in the isolation of multiple crystal forms, it is essential to characterize… read more here.
Keywords: fluconazole; crystal; ray; crystal forms ... See more keywords