Crystal structure and functional characterization of SF216 from Shigella flexneri
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12873
Abstract: Shigella flexneri is a Gram‐negative anaerobic bacterium that causes highly infectious bacterial dysentery in humans. Here, we solved the crystal structure of SF216, a hypothetical protein from the S. flexneri 5a strain M90T, at 1.7… read more here.
Keywords: crystal structure; structure functional; structure; shigella flexneri ... See more keywords
Crystal structure of the human tau PHF core domain VQIINK complexed with the Fab domain of monoclonal antibody Tau2r3
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13791
Abstract: Neurofibrillary tangles formed by abnormally aggregated tau protein are a histopathological feature of tauopathies. A tau aggregation inhibitor is a potential therapeutic agent for tauopathies. In this study, we prepared a monoclonal antibody for tau,… read more here.
Keywords: tau aggregation; crystal structure; domain; monoclonal antibody ... See more keywords
Crystal structure of the Fusarium oxysporum tannase‐like feruloyl esterase FaeC in complex with p‐coumaric acid provides insight into ligand binding
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14615
Abstract: Feruloyl esterases (FAEs) hydrolyze the ester bonds between hydroxycinnamic acids and arabinose residues of plant cell walls and exhibit considerable diversity in terms of substrate specificity. Here, we report the crystal structure of an FAE… read more here.
Keywords: coumaric acid; structure; fusarium oxysporum; tannase like ... See more keywords
A high‐resolution (1.2 Å) crystal structure of the anti‐CRISPR protein AcrIF9
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DOI: 10.1002/2211-5463.12986
Abstract: Prokaryotic adaptive immunity by CRISPR‐Cas systems, which confer resistance to foreign genetic elements, has been used by bacteria to combat viruses. To cope, viruses evolved multiple anti‐CRISPR proteins, which can inhibit system function through various… read more here.
Keywords: crystal structure; high resolution; resolution crystal; anti crispr ... See more keywords
The first crystal structure of a family 45 glycoside hydrolase from a brown‐rot fungus, Gloeophyllum trabeum GtCel45A
Sign Up to like & getrecommendations! Published in 2024 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13774
Abstract: Here we describe the first crystal structure of a beta‐1,4‐endoglucanase from a brown‐rot fungus, Gloeophyllum trabeum GtCel45A, which belongs to subfamily C of glycoside hydrolase family 45 (GH45). GtCel45A is ~ 18 kDa in size and the… read more here.
Keywords: structure; rot fungus; gtcel45a; crystal structure ... See more keywords
Real-space crystal structure analysis by low-dose focal-series TEM imaging of organic materials with near-atomic resolution.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202202088
Abstract: Structural analysis of beam-sensitive materials by transmission electron microscopy (TEM) represents a significant challenge, as high resolution TEM (HRTEM) requires high electron doses that limits its applicability to stable inorganic materials. Beam sensitive materials, such… read more here.
Keywords: resolution; crystal structure; low dose; real space ... See more keywords
Engineering a Lipid Nanoparticle with Atypical Calcium Crystal Structure for Enhanced IFNβ‐Mediated Immunotherapy
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DOI: 10.1002/adma.202419870
Abstract: Immune checkpoint inhibitors have revolutionized cancer therapy; however, many patients exhibit suboptimal responses, which is due to inadequate T cell priming by the innate immune response. Metal ions play a critical role in modulating the… read more here.
Keywords: calcium; cell; tumor; crystal structure ... See more keywords
Impact of Shell Crystal Structure on the Thermal Stability and Photophysical Behavior of Blue Quantum dots
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DOI: 10.1002/adom.202502247
Abstract: Epitaxial shell is vital for enhancing the optoelectronic performance of semiconductor quantum dots (QDs), especially for the wide bandgap blue QDs, yet the shell crystal structure's impact on thermal stability and photophysical behavior remains unexplored.… read more here.
Keywords: shell crystal; crystal structure; stability; thermal stability ... See more keywords
Synthesis of (‐)‐8a epi‐Lentiginosine via Tsuji‐Trost Reaction of d‐Glucose‐Derived Allylic Alcohols and Crystal Structure Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202500103
Abstract: An indolizidine alkaloid, (‐)‐8a‐epi‐lentiginosine was synthesized from d‐glucose using the Pd‐BiPhePhos catalyzed intramolecular Tsuji‐Trost reaction of non‐derivatized allylic alcohol as a key construction of the hydroxylated pyrrolidine ring to give the desired product in good… read more here.
Keywords: epi lentiginosine; tsuji trost; crystal structure; structure ... See more keywords
Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201900271
Abstract: In the present study, a novel series of polyfunctionalized imidazopyrimidines 6a–u and 9a–d were efficiently constructed by a domino reaction between 2‐imino‐6‐substituted‐2,3‐dihydropyrimidin‐4(1H)‐ones 4a–d or 8a–c and 2‐bromoacetophenones 5a–i under mild basic conditions. The synthesized series… read more here.
Keywords: structure adme; crystal structure; adme prediction; activity ... See more keywords
Implications of Crystal Structure on Organotin Carboxylate Photoresists
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DOI: 10.1002/crat.201700081
Abstract: A series of five organotin carboxylates of the type [RSn(O)O2CR’]6 containing n-butyl ligands and carboxylates ranging in size from formate to diphenylacetate were synthesized and examined by single crystal X-ray diffraction. The crystal and packing… read more here.
Keywords: carboxylate; crystal structure; organotin carboxylate; implications crystal ... See more keywords