Crystal structure and functional characterization of SF216 from Shigella flexneri
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12873
Abstract: Shigella flexneri is a Gram‐negative anaerobic bacterium that causes highly infectious bacterial dysentery in humans. Here, we solved the crystal structure of SF216, a hypothetical protein from the S. flexneri 5a strain M90T, at 1.7… read more here.
Keywords: crystal structure; structure functional; structure; shigella flexneri ... See more keywords
Crystal structure of the human tau PHF core domain VQIINK complexed with the Fab domain of monoclonal antibody Tau2r3
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Letters"
DOI: 10.1002/1873-3468.13791
Abstract: Neurofibrillary tangles formed by abnormally aggregated tau protein are a histopathological feature of tauopathies. A tau aggregation inhibitor is a potential therapeutic agent for tauopathies. In this study, we prepared a monoclonal antibody for tau,… read more here.
Keywords: tau aggregation; crystal structure; domain; monoclonal antibody ... See more keywords
Crystal structure of the Fusarium oxysporum tannase‐like feruloyl esterase FaeC in complex with p‐coumaric acid provides insight into ligand binding
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14615
Abstract: Feruloyl esterases (FAEs) hydrolyze the ester bonds between hydroxycinnamic acids and arabinose residues of plant cell walls and exhibit considerable diversity in terms of substrate specificity. Here, we report the crystal structure of an FAE… read more here.
Keywords: coumaric acid; structure; fusarium oxysporum; tannase like ... See more keywords
A high‐resolution (1.2 Å) crystal structure of the anti‐CRISPR protein AcrIF9
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12986
Abstract: Prokaryotic adaptive immunity by CRISPR‐Cas systems, which confer resistance to foreign genetic elements, has been used by bacteria to combat viruses. To cope, viruses evolved multiple anti‐CRISPR proteins, which can inhibit system function through various… read more here.
Keywords: crystal structure; high resolution; resolution crystal; anti crispr ... See more keywords
Real-space crystal structure analysis by low-dose focal-series TEM imaging of organic materials with near-atomic resolution.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202202088
Abstract: Structural analysis of beam-sensitive materials by transmission electron microscopy (TEM) represents a significant challenge, as high resolution TEM (HRTEM) requires high electron doses that limits its applicability to stable inorganic materials. Beam sensitive materials, such… read more here.
Keywords: resolution; crystal structure; low dose; real space ... See more keywords
Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.201900271
Abstract: In the present study, a novel series of polyfunctionalized imidazopyrimidines 6a–u and 9a–d were efficiently constructed by a domino reaction between 2‐imino‐6‐substituted‐2,3‐dihydropyrimidin‐4(1H)‐ones 4a–d or 8a–c and 2‐bromoacetophenones 5a–i under mild basic conditions. The synthesized series… read more here.
Keywords: structure adme; crystal structure; adme prediction; activity ... See more keywords
Implications of Crystal Structure on Organotin Carboxylate Photoresists
Sign Up to like & getrecommendations! Published in 2017 at "Crystal Research and Technology"
DOI: 10.1002/crat.201700081
Abstract: A series of five organotin carboxylates of the type [RSn(O)O2CR’]6 containing n-butyl ligands and carboxylates ranging in size from formate to diphenylacetate were synthesized and examined by single crystal X-ray diffraction. The crystal and packing… read more here.
Keywords: carboxylate; crystal structure; organotin carboxylate; implications crystal ... See more keywords
Au15Ag3(SPhMe2)14 Nanoclusters – Crystal Structure and Insights into Ligand-Induced Variation
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Inorganic Chemistry"
DOI: 10.1002/ejic.201601513
Abstract: Understanding the ligand effects in the nanocluster (NC) range is crucial for tailoring the properties. We herein report on the crystal structure of the Au15Ag3(SPhMe2)14 nanocluster. Compared with the previously reported Au15Au3(SC6H11)14 nanocluster, Au15Ag3(SPhMe2)14 exhibits… read more here.
Keywords: crystal structure; au15ag3 sphme2; ligand induced; induced variation ... See more keywords
Photochemical Synthesis and Characterization of Xenon(VI) Hexafluoridomanganates(IV)
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Inorganic Chemistry"
DOI: 10.1002/ejic.201700054
Abstract: Reactions between XeF2, MnF3 and UV-irradiated elemental F2 in anhydrous HF have yielded [XeF5]2[MnF6] and XeF5MnF5; meanwhile, [XeF5]4[Mn8F36] has been observed as a minor phase upon the crystallization of the product obtained by fluorination of… read more here.
Keywords: crystal structure; mnf6; xef5; xef5 mnf6 ... See more keywords
Crystal structure of phospholipase A2 in complex with 1‐naphthaleneacetic acid
Sign Up to like & getrecommendations! Published in 2018 at "IUBMB Life"
DOI: 10.1002/iub.1924
Abstract: Phospholipase A2 (PLA2) is one of the rate limiting enzymes involved in the production of arachidonic acid, a potent inflammatory mediator. PLA2 is widely distributed all over the animal kingdom. It is also seen in… read more here.
Keywords: crystal structure; phospholipase complex; pla2; phospholipase ... See more keywords
The Pfizer Crystal Structure Database: An essential tool for structure‐based design at Pfizer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.26862
Abstract: Pfizer's Crystal Structure Database (CSDB) is a key enabling technology that allows scientists on structure‐based projects rapid access to Pfizer's vast library of in‐house crystal structures, as well as a significant number of structures imported… read more here.
Keywords: structure database; structure; pfizer; pfizer crystal ... See more keywords