Physicochemical, morphological and thermal evaluation of lyotropic lipidic liquid crystalline nanoparticles: The effect of stimuli-responsive polymeric stabilizer
Sign Up to like & getrecommendations! Published in 2020 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2020.124678
Abstract: Abstract Non-lamellar liquid crystalline nanoparticles are promising drug delivery lipidic nanosystems, stabilized by amphiphilic block copolymers. In the present investigation, the widely used Poloxamer P407 is compared with the innovative stimuli-responsive polycationic block copolymer poly(2-(dimethylamino)ethyl… read more here.
Keywords: crystalline nanoparticles; stabilizer; liquid crystalline; stimuli responsive ... See more keywords
Current potential and challenges in the advances of liquid crystalline nanoparticles as drug delivery systems.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.05.004
Abstract: Lyotropic nonlamellar liquid crystalline nanoparticles (NPs) (LCN), such as cubosomes and hexosomes, are useful tools for applications in drug delivery because of their unique structural properties. LCNs are highly versatile carriers that can be applied… read more here.
Keywords: drug delivery; crystalline nanoparticles; drug; current potential ... See more keywords
Effects of pH of processing‐medium on re‐dispersion of spray dried, crystalline nanoparticles of pure naproxen
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.12.084
Abstract: ABSTRACT Crystalline nanodispersions of naproxen stabilized with hydroxypropyl cellulose were prepared at different pHs both below and above the pKa of the drug. After spray drying together with lactose, the measured particle size of the… read more here.
Keywords: spray; medium dispersion; crystalline nanoparticles; processing medium ... See more keywords
Can spray freeze-drying improve the re-dispersion of crystalline nanoparticles of pure naproxen?
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.061
Abstract: Spray freeze drying (SFD) was used to prepare re-dispersible powders of crystalline, pure-drug nanodispersions of naproxen in lactose and stabilized with hydroxypropyl cellulose. The particle size of the rehydrated powders was determined using static light… read more here.
Keywords: freeze drying; spray; spray freeze; crystalline nanoparticles ... See more keywords
Freeze-dried and re-hydrated liquid crystalline nanoparticles stabilized with disaccharides for drug-delivery of the plectasin derivative AP114 antimicrobial peptide.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2018.03.062
Abstract: Liquid crystalline nanoparticles (LCNPs), e.g. cubosomes and hexosomes, are receiving more and more attraction as drug delivery vehicles. Dry powder formulation that forms LCNPs upon hydration can be advantageous to make new routes of administration… read more here.
Keywords: drug delivery; crystalline nanoparticles; liquid crystalline; antimicrobial peptide ... See more keywords
Approaches to contactless optical thermometer in the NIR spectral range based on Nd3+ doped crystalline nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Luminescence"
DOI: 10.1016/j.jlumin.2016.11.061
Abstract: Abstract The fluorescence kinetics and spectral intensity ratio (FIR) methods for contactless optical temperature measurement in the NIR spectral range with Nd3+ doped YAG micro- and YPO4 nanocrystals are considered and the problems are revealed.… read more here.
Keywords: spectral range; crystalline nanoparticles; contactless optical; doped crystalline ... See more keywords
Magnetic properties of crystalline nanoparticles with different sizes and shapes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Magnetism and Magnetic Materials"
DOI: 10.1016/j.jmmm.2016.10.124
Abstract: Abstract The effects of shape and finite size on the physical behavior of nanostructured antiferromagnetic particles are investigated. They were modeled as ellipsoidal systems which preserve the crystalline structure of the correspondent bulk material. In… read more here.
Keywords: crystalline nanoparticles; magnetic properties; different sizes; properties crystalline ... See more keywords
Hispolon-Loaded Liquid Crystalline Nanoparticles: Development, Stability, In Vitro Delivery Profile, and Assessment of Hepatoprotective Activity in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06796
Abstract: The present work describes the development and characterization of liquid crystalline nanoparticles of hispolon (HP-LCNPs) for treating hepatocellular carcinoma. HP-LCNPs were prepared by a top-down method utilizing GMO as the lipid and Pluronic F-127 as… read more here.
Keywords: hepatocellular carcinoma; stability vitro; crystalline nanoparticles; development ... See more keywords
Epigallocatechin gallate-zinc oxide co-crystalline nanoparticles as an anticancer drug that is non-toxic to normal cells
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c7ra10997k
Abstract: Decreased uptake and cellular accumulation of zinc is a common characteristic in cancer of the liver, pancreas and prostate, because these malignant cells are intolerant to the physiological concentrations of zinc. A tea polyphenol, epigallocatechin-3-gallate… read more here.
Keywords: normal cells; zinc; crystalline nanoparticles; zinc oxide ... See more keywords
Early appearance of crystalline nanoparticles in pulsed laser ablation in liquids dynamics.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr01203f
Abstract: The size and crystallinity of gold and silver nanoparticles during the process of pulsed laser ablation in water (PLAL) is investigated with microsecond and sub-microsecond time resolution. While basic observations have already been established, such… read more here.
Keywords: ablation; crystalline nanoparticles; appearance crystalline; laser ablation ... See more keywords
Insulin- and quercetin-loaded liquid crystalline nanoparticles: implications on oral bioavailability, antidiabetic and antioxidant efficacy.
Sign Up to like & getrecommendations! Published in 2018 at "Nanomedicine"
DOI: 10.2217/nnm-2017-0278
Abstract: AIM The present study reports insulin (INS)- and quercetin (QT)-lyotropic liquid crystalline nanoparticles (LCNPs) with improved bioavailability, antidiabetic and antioxidant efficacy following oral administration. MATERIALS & METHODS The developed INS-QT-LCNPs were evaluated for simulated gastric… read more here.
Keywords: bioavailability antidiabetic; antioxidant efficacy; crystalline nanoparticles; bioavailability ... See more keywords