Crystallization and characterization of small molecular multidrug resistance inhibitor targeting P-glycoprotein, NSC23925 isomers
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DOI: 10.1016/j.molstruc.2019.05.010
Abstract: Abstract The correlation between P-glycoprotein (Pgp) overexpression and multidrug resistance (MDR) in cancer is well-established. Recently, we identified (2-(4-methoxyphenyl)-4-quinolinyl) (2-piperidinyl)methanol (5) (NSC23925) as the most selective and potent MDR inhibitor. NSC23925 binds to Pgp, thus… read more here.
Keywords: characterization small; multidrug resistance; crystallization characterization; multidrug ... See more keywords
Large-Sized Organic Semiconductors: Crystallization, Characterization and Applications
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DOI: 10.1039/d5ce00398a
Abstract: This review explores the growth methods, properties, and applications of large-sized organic single crystals, emphasizing their significance in advanced material technologies such as optoelectronics, nonlinear optics, and radiation detection. The... read more here.
Keywords: sized organic; crystallization characterization; applications large; organic semiconductors ... See more keywords