Integrative/Hybrid Methods Structural Biology: Role of Macromolecular Crystallography.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-2200-6_2
Abstract: Macromolecular crystallography has been central to the emergence and development of structural biology as a scientific discipline. Approximately 90% of the more than 138,000 three-dimensional structures currently available in the Protein Data Bank (PDB) archive,… read more here.
Keywords: structural biology; crystallography; biology; hybrid methods ... See more keywords
X-Ray Crystallography in Structure-Function Characterization of Therapeutic Enzymes.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-7709-9_4
Abstract: Enzymes are key biological macromolecules that support life by accelerating the conversion of target molecules to desired products in many biochemical reactions. Enzymes are characterized by high affinity, specificity and great catalytic efficiency. Owing to… read more here.
Keywords: function characterization; crystallography structure; ray crystallography; crystallography ... See more keywords
Effect of the elastic coefficient heterogeneity and crystallography on the grain growth stagnation
Sign Up to like & getrecommendations! Published in 2021 at "Acta Mechanica"
DOI: 10.1007/s00707-021-02995-6
Abstract: The effect of crystallography and elastic coefficient heterogeneity between a thin film and its substrate has been theoretically investigated on the shear-coupled grain boundary migration in the film. A drag force associated with the elastic… read more here.
Keywords: effect; grain growth; crystallography; film ... See more keywords
Summary of lecture at biophysics and structural biology at synchrotrons workshop Crystallography 101: diffraction theory and space groups
Sign Up to like & getrecommendations! Published in 2019 at "Biophysical Reviews"
DOI: 10.1007/s12551-019-00576-5
Abstract: To determine the three-dimensional structures of proteins, we need to ‘look’ at them using electromagnetic radiation which has a similar wavelength to the interatomic distances in the molecule. These are typically around 1.5 × 10… read more here.
Keywords: structural biology; space; biophysics structural; crystallography ... See more keywords
Deuteration of human carbonic anhydrase for neutron crystallography: Cell culture media, protein thermostability, and crystallization behavior.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.03.008
Abstract: Deuterated proteins and other bio-derived molecules are important for NMR spectroscopy, neutron reflectometry, small angle neutron scattering, and neutron protein crystallography. In the current study we optimized expression media and cell culture conditions to produce… read more here.
Keywords: neutron; cell culture; crystallography; human carbonic ... See more keywords
Predictive micromechanical model for plastic accommodation and crystallography of martensite embryo
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Engineering Science"
DOI: 10.1016/j.ijengsci.2020.103245
Abstract: Abstract It is widely accepted that the lattice transformation strain and plastic shearing of a martensite embryo preset its final lattice orientation. However, the phenomenological theory of martensite crystallography (PTMC) solves an inverse problem where… read more here.
Keywords: martensite embryo; crystallography; plastic accommodation; micromechanical model ... See more keywords
Serial synchrotron and XFEL crystallography for studies of metalloprotein catalysis.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2021.07.007
Abstract: An estimated half of all proteins contain a metal, with these being essential for a tremendous variety of biological functions. X-ray crystallography is the major method for obtaining structures at high resolution of these metalloproteins,… read more here.
Keywords: xfel crystallography; synchrotron; serial synchrotron; crystallography ... See more keywords
Viewpoint: Nanoscale chemistry and crystallography are both the obstacle and pathway to advanced radiation-tolerant materials☆
Sign Up to like & getrecommendations! Published in 2018 at "Scripta Materialia"
DOI: 10.1016/j.scriptamat.2017.05.014
Abstract: Abstract New candidate materials for GenIV or fusion nuclear energy systems, e.g., nanostructured ferritic alloys, are distinguished from older-generation nuclear materials by much smaller feature sizes and complex local nanochemistry and crystallography. Established and perspective… read more here.
Keywords: nanoscale chemistry; chemistry crystallography; chemistry; viewpoint nanoscale ... See more keywords
A toolbox for improving the workflow of NMR crystallography.
Sign Up to like & getrecommendations! Published in 2021 at "Solid state nuclear magnetic resonance"
DOI: 10.1016/j.ssnmr.2021.101761
Abstract: NMR crystallography is a powerful tool with applications in structural characterization and crystal structure verification, to name two. However, applying this tool presents several challenges, especially for industrial users, in terms of consistency, workflow, time… read more here.
Keywords: workflow nmr; crystallography; toolbox improving; nmr crystallography ... See more keywords
Understanding pre-mRNA splicing through crystallography.
Sign Up to like & getrecommendations! Published in 2017 at "Methods"
DOI: 10.1016/j.ymeth.2017.04.023
Abstract: Crystallography is a powerful tool to determine the atomic structures of proteins and RNAs. X-ray crystallography has been used to determine the structure of many splicing related proteins and RNAs, making major contributions to our… read more here.
Keywords: mrna splicing; understanding pre; crystallography; pre mrna ... See more keywords
Exploring structural database use in crystallography: a workshop series of the U.S. National Committee for Crystallography
Sign Up to like & getrecommendations! Published in 2023 at "Powder Diffraction"
DOI: 10.1017/s0885715623000064
Abstract: The U.S. National Committee for Crystallography (USNC/Cr) of the National Academies of Sciences, Engineering, and Medicine provided an online workshop series for researchers on the use, development, and maintenance of crystallographic and structural databases in… read more here.
Keywords: national committee; series; crystallography; committee crystallography ... See more keywords