CSC-3436 sensitizes triple negative breast cancer cells to TRAIL-induced apoptosis through ROS-mediated p38/CHOP/death receptor 5 signaling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology"
DOI: 10.1002/tox.23372
Abstract: Tumor necrosis factor-related apoptosis-induced ligand (TRAIL) shows little or no toxicity in most normal cells and preferentially induces apoptosis in a variety of malignant cells. However, patients develop resistance to TRAIL, therefore, sensitizing agents that… read more here.
Keywords: chop; csc 3436; cells trail; apoptosis ... See more keywords