Antiestrogen Therapy Increases Plasticity and Cancer Stemness of Prolactin-Induced ERα+ Mammary Carcinomas.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-0985
Abstract: Although antiestrogen therapies are successful in many patients with estrogen receptor alpha-positive (ERα+) breast cancer, 25% to 40% fail to respond. Although multiple mechanisms underlie evasion of these treatments, including tumor heterogeneity and drug-resistant cancer… read more here.
Keywords: csc activity; antiestrogen; prolactin induced; cancer ... See more keywords
Reactivated thyroid hormone receptor β attenuates ATC stem cell activity.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine-related cancer"
DOI: 10.1530/erc-22-0306
Abstract: Anaplastic thyroid cancer (ATC) is one of the most aggressive solid cancers in humans, with limited treatment options. Recent studies suggest that cancer stem cell (CSC) activity contributes to therapeutic resistance and recurrence of ATC.… read more here.
Keywords: cell; stem cell; csc activity; expression ... See more keywords