PM2.5 induces EMT and promotes CSC properties by activating Notch pathway in vivo and vitro.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.03.086
Abstract: Fine particulate matter (PM2.5) has been closely linked to increased morbidity and mortality of lung cancer worldwide. However, the role of PM2.5 in the etiology of lung cancer and the mechanism involved in PM2.5 induced… read more here.
Keywords: pm2; csc properties; pathway; cancer ... See more keywords
NEAT1 is Required for the Expression of the Liver Cancer Stem Cell Marker CD44
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21061927
Abstract: CD44, a cancer stem cell (CSC) marker, is required for maintaining CSC properties in hepatocellular carcinoma (HCC). Nuclear enriched abundant transcript 1 (NEAT1), a long noncoding RNA (lncRNA), is an oncogenic driver in HCC. In… read more here.
Keywords: csc; csc properties; marker; expression ... See more keywords