Expression of Programmed Cell Death Ligand in Cutaneous Squamous Cell Carcinoma and Treatment of Locally Advanced Disease With Pembrolizumab
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2016.5118
Abstract: Importance Limited therapies are available in patients with inoperable locally advanced cutaneous squamous cell carcinoma (cSCC). Objective To determine the efficacy of programmed cell death 1 receptor (PD-1) inhibitors in locally advanced cSCC. Design, Setting,… read more here.
Keywords: treatment; expression; pembrolizumab; locally advanced ... See more keywords
Ten-Year Follow-up of Persons With Sun-Damaged Skin Associated With Subsequent Development of Cutaneous Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2021.0372
Abstract: Importance Risk of cutaneous squamous cell carcinoma (cSCC) after the diagnosis of actinic keratosis (AK) has not been studied during long follow-up periods. Objective To estimate the risk up to 10 years and identify risk… read more here.
Keywords: risk; age; cell carcinoma; year ... See more keywords
Lifetime Sunburn Trajectories and Associated Risks of Cutaneous Melanoma and Squamous Cell Carcinoma Among a Cohort of Norwegian Women.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4053
Abstract: Importance To our knowledge, no study has prospectively investigated sunburn patterns over age periods from childhood to adulthood and their associations with skin cancer risk. Objective To identify lifetime trajectories of sunburns and compare the… read more here.
Keywords: cell carcinoma; cscc; squamous cell; melanoma squamous ... See more keywords
Circular RNA profiles and the potential involvement of down‐expression of hsa_circ_0001360 in cutaneous squamous cell carcinogenesis
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13114
Abstract: Circular RNAs (circRNAs) act as sponges of noncoding RNAs and have been implicated in many pathophysiological processes, including tumor development and progression. However, their roles in cutaneous squamous cell carcinoma (cSCC) are not yet well… read more here.
Keywords: circ 0001360; squamous cell; hsa circ; cutaneous squamous ... See more keywords
Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T‐Cell Function and Anti‐PD‐1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T‐Cell‐Incorporated Tumor Organoid Studies
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202502225
Abstract: Cervical squamous cell carcinoma(CSCC) represents formidable challenge in clinical oncology, exacerbated by poor prognosis and resistance to current treatments, including anti‐PD‐1 therapy, highlighting the urgent need for alternative therapeuties. Metabolic characteristics have emerged as potential… read more here.
Keywords: glutamine metabolism; slc25a22; cell; cscc ... See more keywords
A systematic and comprehensive analysis of colorectal squamous cell carcinoma: Implication for diagnosis and treatment.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer medicine"
DOI: 10.1002/cam4.4616
Abstract: BACKGROUND This study was aimed at establishing a nomogram for survival prediction of Colorectal squamous cell carcinoma (CSCC), understanding the molecular pathogenesis, exploring a better treatment, and predicting the potential therapeutic agents. METHODS Surveillance, Epidemiology,… read more here.
Keywords: analysis; cscc; treatment; squamous cell ... See more keywords
Downregulation of HDAC3 by ginsenoside Rg3 inhibits epithelial–mesenchymal transition of cutaneous squamous cell carcinoma through c‐Jun acetylation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28788
Abstract: The metastatic rate of human cutaneous squamous cell carcinoma (CSCC) has increased in recent years. Despite the current advances in therapies, effective treatments remain lacking. Ginsenoside 20(R)‐Rg3 is an effective antitumor monomer extracted from ginseng,… read more here.
Keywords: jun acetylation; rg3; hdac3; cell ... See more keywords
Fibroblast growth factor receptor promotes progression of cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23012
Abstract: Cutaneous squamous cell carcinoma (cSCC) is a keratinocyte‐derived invasive and metastatic tumor of the skin. It is the second‐most commonly diagnosed form of skin cancer striking 200 000 Americans annually. Further, in organ transplant patients, there… read more here.
Keywords: cell carcinoma; squamous cell; fibroblast growth; cutaneous squamous ... See more keywords
Twist1 as a target for prevention of cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23482
Abstract: Cutaneous squamous cell carcinoma (cSCC) represents an important clinical problem requiring novel approaches for both prevention and treatment. The transcription factor, Twist‐related protein 1 (Twist1), has been identified as having a key mechanistic role in… read more here.
Keywords: cell; cutaneous squamous; cscc; prevention ... See more keywords
Proline‐rich 11 (PRR11) promotes the progression of cutaneous squamous cell carcinoma by activating the EGFR signaling pathway
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23510
Abstract: Cutaneous squamous cell carcinoma (cSCC) is one of the most common skin malignancies, and its incidence rate is increasing worldwide. Proline‐rich 11 (PRR11) has been reported to be involved in the occurrence and development of… read more here.
Keywords: cell; cell carcinoma; cutaneous squamous; cscc ... See more keywords
T1 mapping and extracellular volume fraction measurement to evaluate the poor-prognosis factors in patients with cervical squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "NMR in biomedicine"
DOI: 10.1002/nbm.4918
Abstract: PURPOSE To evaluate the clinical feasibility of T1 mapping and extracellular volume fraction (ECV) measurement in assessing prognostic factors in patients with cervical squamous cell carcinoma (CSCC). MATERIALS AND METHODS A total of 117 CSCC… read more here.
Keywords: extracellular volume; mapping extracellular; cscc; volume fraction ... See more keywords