Epigenetic regulation of cancer stem cell formation and maintenance
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33398
Abstract: Cancerous tumours contain a rare subset of cells with stem‐like properties that are termed cancer stem cells (CSCs). CSCs are defined by their ability to divide both symmetrically and asymmetrically, to initiate new tumour growth… read more here.
Keywords: cancer; epigenetic regulation; cancer stem; cscs ... See more keywords
Detention and Identification of Cancer Stem Cells in Esophageal Squamous Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0377-2_14
Abstract: Cancer stem cells (CSCs) are a small subpopulation of cells associated with cancer initiation, progression, metastasis, therapy resistant, and recurrence. In esophageal squamous cell carcinoma (ESCC), several cell surface and intracellular markers, for example, CD44,… read more here.
Keywords: cell; cscs; identification; cancer ... See more keywords
A medicinal chemistry perspective on salinomycin as a potent anticancer and anti-CSCs agent.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.12.057
Abstract: Tumors are phenotypically heterogeneous and include a small sub-population of cancer cells (2-5% of the tumor mass) with stem-cell like properties. The cancer stem cell hypothesis postulates that the cancer stem cells (CSCs) show the… read more here.
Keywords: cscs; medicinal chemistry; chemistry; cancer cells ... See more keywords
Bioinformatics analysis and verification of molecular targets in ovarian cancer stem-like cells
Sign Up to like & getrecommendations! Published in 2020 at "Heliyon"
DOI: 10.1016/j.heliyon.2020.e04820
Abstract: Background Epithelial ovarian cancer (EOC) is a lethal and aggressive gynecological malignancy. Despite recent advances, existing therapies are challenged by a high relapse rate, eventually resulting in disease recurrence and chemoresistance. Emerging evidence indicates that… read more here.
Keywords: cancer stem; cscs; analysis; ovarian cancer ... See more keywords
Theaflavin-3, 3'-digallate inhibits ovarian cancer stem cells via suppressing Wnt/β-Catenin signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of functional foods"
DOI: 10.1016/j.jff.2018.09.021
Abstract: Recent evidence indicates that ovarian cancer stem cells (CSCs) are responsible for ovarian cancer recurrence and drug resistance, resulting in the low long-term survival rate of patients with advanced ovarian cancer. We aimed to study… read more here.
Keywords: cancer stem; cscs; ovarian cancer; theaflavin digallate ... See more keywords
Responses of hyperiid (Amphipoda) communities to monsoon reversal in the central South China Sea
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Oceanography"
DOI: 10.1016/j.pocean.2020.102440
Abstract: Abstract Significant seasonal variations in surface circulation are driven by the East Asian Monsoon in the South China Sea (SCS). Seasonal variations in copepod and hyperiid communities following the monsoon have been reported. The mechanisms… read more here.
Keywords: water; cscs; hyperiid; south china ... See more keywords
High-Resolution In Situ High-Content Imaging of 3D-Bioprinted Single Breast Cancer Spheroids for Advanced Quantification of Benzo(a)pyrene Carcinogen-Induced Breast Cancer Stem Cells.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c17877
Abstract: Cancer stem cells (CSCs), also known as tumor-initiating cells, are critically correlated with carcinogenesis and are strongly affected by the environmental factors. Environmental carcinogens, such as benzo(a)pyrene (BaP), are associated with the overproduction of CSCs… read more here.
Keywords: cancer stem; breast; breast cancer; cscs ... See more keywords
Differentiation of Cancer Stem Cells through Nanoparticle Surface Engineering.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.0c05589
Abstract: Cancer stem cells (CSCs) are a crucial therapeutic target because of their role in resistance to chemo- and radiation therapy, metastasis, and tumor recurrence. Differentiation therapy presents a potential strategy for "defanging" CSCs. To date,… read more here.
Keywords: stem cells; cancer stem; differentiation; cscs ... See more keywords
Retinoic Acid-Loaded Dendritic Polyglycerol-Conjugated Gold Nanostars for Targeted Photothermal Therapy in Breast Cancer Stem Cells.
Sign Up to like & getrecommendations! Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.1c05452
Abstract: The existence of cancer stem cells (CSCs) poses a major obstacle for the success of current cancer therapies, especially the fact that non-CSCs can spontaneously turn into CSCs, which lead to the failure of the… read more here.
Keywords: stem cells; dendritic polyglycerol; cancer stem; cscs ... See more keywords
Visualization and targeting of LGR5+ human colon cancer stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature22081
Abstract: The cancer stem cell (CSC) theory highlights a self-renewing subpopulation of cancer cells that fuels tumour growth. The existence of human CSCs is mainly supported by xenotransplantation of prospectively isolated cells, but their clonal dynamics… read more here.
Keywords: cancer stem; cscs; lgr5 cscs; targeting lgr5 ... See more keywords
KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/β-catenin signalling
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15146
Abstract: Human colorectal cancer stem cells (CSCs) are tumour initiating cells that can self-renew and are highly tumorigenic and chemoresistant. While genetic mutations associated with human colorectal cancer development are well-known, little is known about how… read more here.
Keywords: cancer stem; cscs; colorectal cancer; human colorectal ... See more keywords