Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells
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DOI: 10.1126/scitranslmed.abq6024
Abstract: Weak immunogenicity of tumor cells is a root cause for the ultimate failure of immunosurveillance and immunotherapy. Although tumor evolution can be shaped by immunoediting toward a less immunogenic phenotype, mechanisms governing the initial immunogenicity… read more here.
Keywords: cell; tumorigenic cells; immunotherapy; immunogenicity ... See more keywords