Splenic NKG2D confers resilience versus susceptibility in mice after chronic social defeat stress: beneficial effects of (R)-ketamine
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-019-01092-z
Abstract: The spleen is a large immune organ that plays a key role in the immune system. The precise molecular mechanisms underlying the relationship between the spleen and stress-related psychiatric disorders are unknown. Here we investigated… read more here.
Keywords: susceptible mice; susceptibility; splenic nkg2d; csds ... See more keywords
Cortical Spreading Depolarizations in a Mouse Model of Subarachnoid Hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Neurocritical Care"
DOI: 10.1007/s12028-021-01397-9
Abstract: Background Cortical spreading depolarizations (CSDs) are associated with worse outcomes in patients with aneurysmal subarachnoid hemorrhage (SAH). Animal models are required to assess whether CSDs can worsen outcomes or are an epiphenomenon; however, little is… read more here.
Keywords: cortical spreading; mice; injection; csds ... See more keywords
Effectiveness of waste steel slag powder on the strength development and associated micro-mechanisms of cement-stabilized dredged sludge
Sign Up to like & getrecommendations! Published in 2020 at "Construction and Building Materials"
DOI: 10.1016/j.conbuildmat.2019.117975
Abstract: Abstract Waste steel slag is an industrial by-product during the process of steelmaking, and it is usually stacked in steelmaking plants. Employing steel slag in treating dredged sludge (DS) would be an economic and environmental… read more here.
Keywords: strength; steel slag; strength development; csds ... See more keywords
Hierarchical Status Predicts Behavioral Vulnerability and Nucleus Accumbens Metabolic Profile Following Chronic Social Defeat Stress
Sign Up to like & getrecommendations! Published in 2017 at "Current Biology"
DOI: 10.1016/j.cub.2017.06.027
Abstract: Extensive data highlight the existence of major differences in individuals' susceptibility to stress [1-4]. While genetic factors [5, 6] and exposure to early life stress [7, 8] are key components for such neurobehavioral diversity, intriguing… read more here.
Keywords: status; csds; vulnerability; chronic social ... See more keywords
Cannabinoid receptor 1 signalling modulates stress susceptibility and microglial responses to chronic social defeat stress
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01283-0
Abstract: Psychosocial stress is one of the main environmental factors contributing to the development of psychiatric disorders. In humans and rodents, chronic stress is associated with elevated inflammatory responses, indicated by increased numbers of circulating myeloid… read more here.
Keywords: cnr1 mice; csds; cannabinoid receptor; stress ... See more keywords
The potential of substance P to initiate and perpetuate cortical spreading depression (CSD) in rat in vivo
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36330-2
Abstract: The tachykinin substance P (SP) increases neuronal excitability, participates in homeostatic control, but induces brain oedema after stroke or trauma. We asked whether SP is able to induce cortical spreading depression (CSD) which often aggravates… read more here.
Keywords: substance; spreading depression; depression csd; csds ... See more keywords
Synergistic consequences of early-life social isolation and chronic stress impact coping and neural mechanisms underlying male prairie vole susceptibility and resilience
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.931549
Abstract: Chronic stress can be challenging, lead to maladaptive coping strategies, and cause negative mental and physical health outcomes. Early-life adversity exposes developing young to physical or psychological experiences that risks surpassing their capacity to effectively… read more here.
Keywords: stress; csds; early life; isolation ... See more keywords
Decreased Colonic Guanylin/Uroguanylin Expression and Dried Stool Property in Mice With Social Defeat Stress
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.599582
Abstract: Psychological stress is deeply involved in the pathophysiology of not only mental illness but also functional gastrointestinal disorders. In the present study, we examined the relationship between psychological stress and abnormality of stool properties, focusing… read more here.
Keywords: expression ugn; csds; guanylin uroguanylin; stress ... See more keywords