Multiple E3s promote the degradation of histone H3 variant Cse4
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08923-w
Abstract: The histone H3-like protein Cse4/CENP-A acts as a key molecular marker that differentiates the special centromeric chromatin structures from bulk nucleosomes. As altered Cse4/CENP-A activity leads to genome instability, it is pivotal to understand the… read more here.
Keywords: cse4; degradation; e3s promote; multiple e3s ... See more keywords
Methylation of CENP-A/Cse4 on arginine 143 and lysine 131 regulates kinetochore stability in yeast
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DOI: 10.1093/genetics/iyad028
Abstract: Abstract Post-translational modifications on histones are well known to regulate chromatin structure and function, but much less information is available on modifications of the centromeric histone H3 variant and their effect at the kinetochore. Here,… read more here.
Keywords: methylation; lysine 131; arginine 143; cenp cse4 ... See more keywords
Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008597
Abstract: Restricting the localization of the histone H3 variant CENP-A (Cse4 in yeast, CID in flies) to centromeres is essential for faithful chromosome segregation. Mislocalization of CENP-A leads to chromosomal instability (CIN) in yeast, fly and… read more here.
Keywords: cse4; proteolysis; mislocalization; scf ... See more keywords