A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noac054
Abstract: Abstract Background Leptomeningeal disease (LMD) occurs as a late complication of several human cancers and has no rationally designed treatment options. A major barrier to developing effective therapies for LMD is the lack of cell-based… read more here.
Keywords: vitro vivo; csf ctcs; melanoma; patient derived ... See more keywords
Detection, molecular profiling and culture of CSF-CTCs in leptomeningeal disease (LMDz) in melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e21543
Abstract: e21543Background: Approx. 5% of melanoma-associated brain tumor cases also develop LMDz. Patients with LMDz have devastating survival outcome, and currently there is no effective treatment. The aim... read more here.
Keywords: culture csf; detection molecular; molecular profiling; ctcs leptomeningeal ... See more keywords