Evidence of altered Th17 pathway signatures in the cerebrospinal fluid of patients with Guillain Barré Syndrome
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DOI: 10.1016/j.jocn.2020.03.010
Abstract: Data indexing the contribution of various immuno-inflammatory components in the cerebrospinal fluid (CSF) towards the pathophysiology of Guillain Barré Syndrome (GBS) are limited. Th17 pathway plays crucial role in many immune mediated disorders of the… read more here.
Keywords: th17 pathway; csf patients; guillain barr; patients gbs ... See more keywords
Proteomic Analysis of CSF from Patients with Leptomeningeal Melanoma Metastases Identifies Signatures Associated with Disease Progression and Therapeutic Resistance
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DOI: 10.1158/1078-0432.ccr-19-2840
Abstract: Purpose: The development of leptomeningeal melanoma metastases (LMM) is a rare and devastating complication of the late-stage disease, for which no effective treatments exist. Here, we performed a multi-omics analysis of the cerebrospinal fluid (CSF)… read more here.
Keywords: analysis; csf; melanoma metastases; leptomeningeal melanoma ... See more keywords
Biomarkers of Neurodegeneration in Autoimmune-Mediated Encephalitis
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DOI: 10.3389/fneur.2018.00668
Abstract: Progranulin (PGRN), Total-Tau (t-tau), and Neurofilament light chain (NfL) are well known biomarkers of neurodegeneration. The objective of the present study was to investigate whether these parameters represent also biomarkers in autoimmune-mediated Encephalitis (AE) and… read more here.
Keywords: csf patients; tau; mediated encephalitis; autoimmune mediated ... See more keywords