Dipeptides in CSF and plasma: diagnostic and therapeutic potential in neurological diseases
Sign Up to like & getrecommendations! Published in 2024 at "Amino Acids"
DOI: 10.1007/s00726-024-03434-1
Abstract: Dipeptides (DPs), composed of two amino acids (AAs), hold significant therapeutic potential but remain underexplored. Given the crucial role of AAs in central nervous system (CNS) function, this study investigated the presence of DPs in… read more here.
Keywords: neurological diseases; therapeutic potential; dps; csf ... See more keywords
Assessment of lipophilic fluorescence products in β-amyloid-induced cognitive decline: A parallel track in hippocampus, CSF, plasma and erythrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2021.111645
Abstract: BACKGROUND Oxidative stress implicates in Alzheimer's disease (AD) pathophysiology, and associates with the creation of end products of free radical reactions, are known as lipophilic fluorescent products (LFPs). This study aimed to evaluate the probable… read more here.
Keywords: csf plasma; fluorescence; plasma erythrocytes; hippocampus ... See more keywords
Proteomic Signatures of Epigenetic Age in African Green Monkey Cerebrospinal Fluid and Plasma
Sign Up to like & getrecommendations! Published in 2025 at "Aging Cell"
DOI: 10.1111/acel.70168
Abstract: Strategies to slow the aging process or mitigate its consequences on health rely on the validation of minimally‐invasive biomarkers of aging that can be used to track aging and test the effectiveness of antiaging interventions.… read more here.
Keywords: epigenetic age; african green; csf plasma; proteomic signatures ... See more keywords
Tau PET correlates with different Alzheimer’s disease‐related features compared to CSF and plasma p‐tau biomarkers
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202114398
Abstract: PET, CSF and plasma biomarkers of tau pathology may be differentially associated with Alzheimer's disease (AD)‐related demographic, cognitive, genetic and neuroimaging markers. We examined 771 participants with normal cognition, mild cognitive impairment or dementia from… read more here.
Keywords: csf plasma; tau pet; plasma; pathology ... See more keywords
Safety and Feasibility of Lin- Cells Administration to ALS Patients: A Novel View on Humoral Factors and miRNA Profiles
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19051312
Abstract: Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular endothelial growth… read more here.
Keywords: als patients; lin cells; csf plasma; cells administration ... See more keywords
Is the Brain Undernourished in Alzheimer’s Disease?
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14091872
Abstract: Cerebrospinal fluid (CSF) amino acid (AA) levels and CSF/plasma AA ratios in Alzheimer Disease (AD) in relation to nutritional state are not known. Methods: In 30 fasting patients with AD (46% males, 74.4 ± 8.2… read more here.
Keywords: nutritional state; csf; csf plasma; alzheimer disease ... See more keywords