Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production
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DOI: 10.1016/j.ebiom.2018.11.062
Abstract: Background Type I IFN-based therapies against solid malignancies have yielded only limited success. How IFN affects tumor-associated macrophage (TAM) compartment to impact the therapeutic outcomes are not well understood. Methods The effect of an IFN-inducer… read more here.
Keywords: type ifn; csf signaling; ifn; tumor ... See more keywords