CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis
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DOI: 10.1186/s12974-019-1397-4
Abstract: BackgroundMicroglia are resident macrophages of the central nervous system (CNS) locally maintained through colony-stimulating factor 1 receptor (CSF1R) signaling. Microglial depletion via CSF1R inactivation improves cognition in mouse models of neuroinflammation, but limits virologic control… read more here.
Keywords: csf1r; virologic control; infection; cns ... See more keywords