Dimerization energetics of curli fiber subunits CsgA and CsgB
Sign Up to like & getrecommendations! Published in 2019 at "npj Computational Materials"
DOI: 10.1038/s41524-019-0164-5
Abstract: Curli fibers are functional amyloids that exhibit strong adhesion and robust self-assembly as biofilm structural components; however, the binding energetics and mechanical properties of wild-type curli are not well understood. To address this, we present… read more here.
Keywords: subunits csga; curli; csga; csga csgb ... See more keywords
Dynamic biofilm architecture confers individual and collective mechanisms of viral protection
Sign Up to like & getrecommendations! Published in 2017 at "Nature microbiology"
DOI: 10.1038/s41564-017-0050-1
Abstract: In nature, bacteria primarily live in surface-attached, multicellular communities, termed biofilms1–6. In medical settings, biofilms cause devastating damage during chronic and acute infections; indeed, bacteria are often viewed as agents of human disease7. However, bacteria… read more here.
Keywords: protection; biofilm architecture; csga; phage ... See more keywords
NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64135-9
Abstract: The biofilms of Enterobacteriaceae are fortified by assembly of curli amyloid fibres on the cell surface. Curli not only provides structural reinforcement, but also facilitates surface adhesion. To prevent toxic intracellular accumulation of amyloid precipitate,… read more here.
Keywords: secretion; csga; nmr insights; curli subunit ... See more keywords