Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion
Sign Up to like & getrecommendations! Published in 2022 at "Nature Communications"
DOI: 10.1101/2022.10.20.513119
Abstract: In this work, the authors show that the phase separation of a cell surface-associated protein called CsgF is critical to mediate the secretion and assembly of the amyloidogenic curli subunits. Curli are functional amyloids present… read more here.
Keywords: csgf; secretion; curli; cell surface ... See more keywords
Cryo-EM structure of the nonameric CsgG-CsgF complex and its implications for controlling curli biogenesis in Enterobacteriaceae
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DOI: 10.1371/journal.pbio.3000748
Abstract: Curli play critical roles in biofilm formation, host cell adhesion, and colonization of inert surfaces in many Enterobacteriaceae. In Escherichia coli, curli biogenesis requires 7 curli-specific gene (csg) products—CsgA through G—working in concert. Of them,… read more here.
Keywords: csgg; cryo structure; csgf; curli biogenesis ... See more keywords